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Dcdc2c doublecortin domain containing 2C [ Mus musculus (house mouse) ]

Gene ID: 68511, updated on 3-Apr-2024

Summary

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Official Symbol
Dcdc2cprovided by MGI
Official Full Name
doublecortin domain containing 2Cprovided by MGI
Primary source
MGI:MGI:1915761
See related
Ensembl:ENSMUSG00000020633 AllianceGenome:MGI:1915761
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110015M06Rik
Summary
Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and sperm flagellum. Predicted to be active in microtubule and microtubule organizing center. Orthologous to human DCDC2C (doublecortin domain containing 2C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 3.9) See more
Orthologs
human all
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Genomic context

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Location:
12 A2; 12 10.94 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (28487794..28602941, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (28437795..28552942, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46326 Neighboring gene predicted gene, 25564 Neighboring gene allantoicase Neighboring gene collectin sub-family member 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The doublecortin gene family and disorders of neuronal structure. Dijkmans TF, et al. Cent Nerv Syst Agents Med Chem, 2010 Mar. PMID 20236041
  2. The evolving doublecortin (DCX) superfamily. Reiner O, et al. BMC Genomics, 2006 Jul 26. PMID 16869982, Free PMC Article
  3. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
  
located_in sperm flagellum ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
doublecortin domain-containing protein 2C
Names
putative doublecortin domain-containing protein ENSP00000382097 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177964.2 → NP_001171435.2  doublecortin domain-containing protein 2C isoform 4

    See identical proteins and their annotated locations for NP_001171435.2

    Status: VALIDATED

    Source sequence(s)
    AC165283, AK003729
    UniProtKB/Swiss-Prot
    Q9D1B8
    Related
    ENSMUST00000189735.7
    Conserved Domains (1) summary
    cl28922
    Location:1 → 45
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  2. NM_001373956.1 → NP_001360885.1  doublecortin domain-containing protein 2C isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC159197, AC165283
    UniProtKB/TrEMBL
    A0AA74KSJ0, A0AA74KT76
    Related
    ENSMUSP00000159704.1, ENSMUST00000249337.1
    Conserved Domains (1) summary
    cl28922
    Location:16 → 94
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  3. NM_001373957.1 → NP_001360886.1  doublecortin domain-containing protein 2C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC165283
    UniProtKB/Swiss-Prot
    Q9D1B8
    Conserved Domains (1) summary
    cl28922
    Location:16 → 94
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  4. NM_001373958.1 → NP_001360887.1  doublecortin domain-containing protein 2C isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC165283
    UniProtKB/Swiss-Prot
    Q9D1B8
    Conserved Domains (1) summary
    cl28922
    Location:16 → 94
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  5. NM_001412102.1 → NP_001399031.1  doublecortin domain-containing protein 2C isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC159197, AC165283
    UniProtKB/TrEMBL
    A0A1Y7VLK4
    Related
    ENSMUSP00000152233.2, ENSMUST00000221349.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    28487794..28602941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157602.1 → XP_036013495.1  doublecortin domain-containing protein 2C isoform X3

    Conserved Domains (1) summary
    cl28922
    Location:1 → 45
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  2. XM_017315166.1 → XP_017170655.1  doublecortin domain-containing protein 2C isoform X1

    UniProtKB/TrEMBL
    A0AA74KT19
    Related
    ENSMUSP00000159706.1, ENSMUST00000249339.1
    Conserved Domains (1) summary
    cl28922
    Location:16 → 94
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  3. XM_017315167.1 → XP_017170656.1  doublecortin domain-containing protein 2C isoform X2

    Conserved Domains (1) summary
    cl28922
    Location:1 → 45
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D1B8.2 GenPept UniProtKB/Swiss-Prot:Q9D1B8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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