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Cgref1 cell growth regulator with EF hand domain 1 [ Mus musculus (house mouse) ]

Gene ID: 68567, updated on 23-Jul-2021

Summary

Official Symbol
Cgref1provided by MGI
Official Full Name
cell growth regulator with EF hand domain 1provided by MGI
Primary source
MGI:MGI:1915817
See related
Ensembl:ENSMUSG00000029161
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CGR1; Cgr11; AW045201; 1110004G24Rik
Expression
Biased expression in duodenum adult (RPKM 402.2), kidney adult (RPKM 154.0) and 5 other tissues See more
Orthologs
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Genomic context

See Cgref1 in Genome Data Viewer
Location:
5; 5 B1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31090487..31102824, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (30933143..30945480, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (31235516..31247853, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene elastin microfibril interfacer 1 Neighboring gene ketohexokinase Neighboring gene abhydrolase domain containing 1 Neighboring gene prolactin regulatory element binding Neighboring gene transcription factor 23

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cell growth regulator with EF hand domain protein 1
Names
cell growth regulatory gene 11 protein
cell growth regulatory with EF-hand domain
hydrophobestin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160149.1NP_001153621.1  cell growth regulator with EF hand domain protein 1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001153621.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AK003420, BQ043218, CB202031
    UniProtKB/Swiss-Prot
    Q8R1U2
    Conserved Domains (1) summary
    pfam13499
    Location:76143
    EF-hand_7; EF-hand domain pair
  2. NM_026770.2NP_081046.2  cell growth regulator with EF hand domain protein 1 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC109606
    Consensus CDS
    CCDS51454.1
    Related
    ENSMUSP00000031051.7, ENSMUST00000031051.8

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    31090487..31102824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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