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Pfn3 profilin 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685936, updated on 6-May-2021

Summary

Official Symbol
Pfn3provided by RGD
Official Full Name
profilin 3provided by RGD
Primary source
RGD:1587838
See related
Ensembl:ENSRNOG00000047752
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Orthologs
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Genomic context

See Pfn3 in Genome Data Viewer
Location:
17p14
Exon count:
1
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9217595..9218122)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9746485..9747012)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor kinase 6 Neighboring gene coagulation factor XII Neighboring gene solute carrier family 34 member 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of actin filament bundle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
profilin-3
Names
profilin III

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109487.1NP_001102957.1  profilin-3

    See identical proteins and their annotated locations for NP_001102957.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474032
    UniProtKB/Swiss-Prot
    M0RCP6
    Related
    ENSRNOP00000067371.1, ENSRNOT00000072298.1
    Conserved Domains (1) summary
    cd00148
    Location:3137
    PROF; Profilin binds actin monomers, membrane polyphosphoinositides such as PI(4,5)P2, and poly-L-proline. Profilin can inhibit actin polymerization into F-actin by binding to monomeric actin (G-actin) and terminal F-actin subunits, but - as a regulator of the ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    9217595..9218122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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