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Etnppl ethanolamine-phosphate phospho-lyase [ Rattus norvegicus (Norway rat) ]

Gene ID: 687071, updated on 5-Mar-2024

Summary

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Official Symbol
Etnpplprovided by RGD
Official Full Name
ethanolamine-phosphate phospho-lyaseprovided by RGD
Primary source
RGD:1590098
See related
Ensembl:ENSRNOG00000045743 AllianceGenome:RGD:1590098
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ethanolamine-phosphate phospho-lyase activity. Predicted to be located in mitochondrion. Orthologous to human ETNPPL (ethanolamine-phosphate phospho-lyase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 177.4), Liver (RPKM 176.2) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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Location:
2q43
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (221847210..221868827)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (219173048..219194646)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (235738377..235760351)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene collagen type XXV alpha 1 chain Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC103691705 Neighboring gene uncharacterized LOC134485967 Neighboring gene oligosaccharyltransferase complex non-catalytic subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine. Veiga-da-Cunha M, et al. J Biol Chem, 2012 Mar 2. PMID 22241472, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ethanolamine-phosphate phospho-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ethanolamine-phosphate phospho-lyase activity ISO
Inferred from Sequence Orthology
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ethanolamine-phosphate phospho-lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    221847210..221868827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003749396.6 → XP_003749444.1  ethanolamine-phosphate phospho-lyase isoform X1

    UniProtKB/TrEMBL
    M0R7F6
    Related
    ENSRNOP00000065383.2
    Conserved Domains (2) summary
    cd00610
    Location:26 → 433
    OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
    COG0160
    Location:11 → 437
    GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]

  2. XM_039103848.2 → XP_038959776.1  ethanolamine-phosphate phospho-lyase isoform X2

    Conserved Domains (1) summary
    PRK06148
    Location:2 → 263
    PRK06148; hypothetical protein; Provisional

  3. XM_039103849.1 → XP_038959777.1  ethanolamine-phosphate phospho-lyase isoform X2

    Conserved Domains (1) summary
    PRK06148
    Location:2 → 263
    PRK06148; hypothetical protein; Provisional
Nucleotide Protein Strain
Heading Accession and Version

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