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Dnai1 dynein axonemal intermediate chain 1 [ Mus musculus (house mouse) ]

Gene ID: 68922, updated on 26-Jun-2021

Summary

Official Symbol
Dnai1provided by MGI
Official Full Name
dynein axonemal intermediate chain 1provided by MGI
Primary source
MGI:MGI:1916172
See related
Ensembl:ENSMUSG00000061322
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dnaic1; BB124644; b2b1526C; b2b1526Clo; 1110066F04Rik
Expression
Biased expression in testis adult (RPKM 28.5), bladder adult (RPKM 10.6) and 5 other tissues See more
Orthologs
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Genomic context

See Dnai1 in Genome Data Viewer
Location:
4; 4 A5
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (41569731..41638158)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (41569647..41638158)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (41516827..41585191)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 219, member A, opposite strand Neighboring gene family with sequence similarity 219, member A Neighboring gene predicted gene 12404 Neighboring gene predicted gene 12405 Neighboring gene energy homeostasis associated Neighboring gene ciliary neurotrophic factor receptor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dynein heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables dynein light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cilium movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cilium movement ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within determination of left/right symmetry IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in determination of left/right symmetry ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within epithelial cilium movement involved in extracellular fluid movement IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in insulin receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in outer dynein arm assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in outer dynein arm assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in 9+2 motile cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cilium ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of dynein complex IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
part_of outer dynein arm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of outer dynein arm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dynein axonemal intermediate chain 1; dynein intermediate chain 1, axonemal
Names
axonemal dynein intermediate chain 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175138.4NP_780347.2  dynein axonemal intermediate chain 1

    See identical proteins and their annotated locations for NP_780347.2

    Status: VALIDATED

    Source sequence(s)
    AK047808, CD775688
    Consensus CDS
    CCDS18066.1
    UniProtKB/Swiss-Prot
    Q8C0M8
    UniProtKB/TrEMBL
    A2ANP4
    Related
    ENSMUSP00000100028.4, ENSMUST00000102963.10
    Conserved Domains (3) summary
    COG2319
    Location:321679
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:336382
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:354612
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    41569731..41638158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164398.1XP_036020291.1  dynein intermediate chain 1, axonemal isoform X1

    Conserved Domains (2) summary
    COG2319
    Location:143501
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:158204
    7WD40; WD40 repeat [structural motif]

RNA

  1. XR_390339.5 RNA Sequence

  2. XR_390340.5 RNA Sequence

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