U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rpl38 ribosomal protein L38 [ Rattus norvegicus (Norway rat) ]

Gene ID: 689284, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Rpl38provided by RGD
Official Full Name
ribosomal protein L38provided by RGD
Primary source
RGD:1305573
See related
Ensembl:ENSRNOG00000066047 AllianceGenome:RGD:1305573
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribonucleoprotein complex assembly. Predicted to act upstream of or within several processes, including 90S preribosome assembly; middle ear morphogenesis; and sensory perception of sound. Part of cytosolic large ribosomal subunit. Orthologous to human RPL38 (ribosomal protein L38). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 2403.4), Thymus (RPKM 2293.0) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
10q32.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (100200414..100204070)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (99701330..99705004)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (103198424..103202059)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480723 Neighboring gene keratin-associated protein 4-5-like Neighboring gene tweety family member 2 Neighboring gene small nucleolar RNA SNORA67 Neighboring gene dynein, axonemal, intermediate chain 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse. Noben-Trauth K, et al. J Biol Chem, 2011 Jan 28. PMID 21062742, Free PMC Article
  2. The primary structure of rat ribosomal protein L38. Kuwano Y, et al. Biochem Biophys Res Commun, 1991 Mar 15. PMID 1840484
  3. Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 60 S ribosomal subunit proteins La, Lb, Lf, P1, P2, L13', L14, L18', L20, and L38. Tsurugi K, et al. J Biol Chem, 1978 Feb 10. PMID 621213
  4. Characterization of the proteome, diseases and evolution of the human postsynaptic density. Bayés A, et al. Nat Neurosci, 2011 Jan. PMID 21170055, Free PMC Article
  5. Structural snapshots of actively translating human ribosomes. Behrmann E, et al. Cell, 2015 May 7. PMID 25957688, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC125176

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within 90S preribosome assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within axial mesoderm development ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within middle ear morphogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ossification ISO
Inferred from Sequence Orthology
more info
  
involved_in protein-RNA complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of translation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within sensory perception of sound ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within skeletal system development ISO
Inferred from Sequence Orthology
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of eukaryotic 80S initiation complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
large ribosomal subunit protein eL38
Names
60S ribosomal protein L38

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077592.1 → NP_001071060.1  large ribosomal subunit protein eL38

    See identical proteins and their annotated locations for NP_001071060.1

    Status: PROVISIONAL

    Source sequence(s)
    BC101933
    UniProtKB/Swiss-Prot
    P63174, Q3T1G5
    UniProtKB/TrEMBL
    A6HKI5
    Related
    ENSRNOP00000088903.1, ENSRNOT00000095224.1
    Conserved Domains (1) summary
    pfam01781
    Location:2 → 68
    Ribosomal_L38e; Ribosomal L38e protein family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    100200414..100204070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008768393.3 → XP_008766615.1  large ribosomal subunit protein eL38 isoform X1

    See identical proteins and their annotated locations for XP_008766615.1

    UniProtKB/Swiss-Prot
    P63174, Q3T1G5
    UniProtKB/TrEMBL
    A6HKI5
    Conserved Domains (1) summary
    pfam01781
    Location:2 → 68
    Ribosomal_L38e; Ribosomal L38e protein family

  2. XM_039086868.2 → XP_038942796.1  large ribosomal subunit protein eL38 isoform X1

    UniProtKB/Swiss-Prot
    P63174, Q3T1G5
    UniProtKB/TrEMBL
    A6HKI5
    Conserved Domains (1) summary
    pfam01781
    Location:2 → 68
    Ribosomal_L38e; Ribosomal L38e protein family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P63174.2 GenPept UniProtKB/Swiss-Prot:P63174

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous