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Zfp707 zinc finger protein 707 [ Mus musculus (house mouse) ]

Gene ID: 69020, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp707provided by MGI
Official Full Name
zinc finger protein 707provided by MGI
Primary source
MGI:MGI:1916270
See related
Ensembl:ENSMUSG00000034429 AllianceGenome:MGI:1916270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500031N24Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in pancreas epithelium. Orthologous to human ZNF707 (zinc finger protein 707). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver adult (RPKM 12.1), colon adult (RPKM 10.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 D3; 15 35.17 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75840972..75847717)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75969123..75975868)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39034 Neighboring gene predicted gene, 53898 Neighboring gene eukaryotic translation initiation factor 2, subunit 3, pseudogene 1 Neighboring gene coiled-coil domain containing 166 Neighboring gene mitogen-activated protein kinase 15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Mu X, et al. Nucleic Acids Res, 2001 Dec 15. PMID 11812828, Free PMC Article
  2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 707

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081065.2 → NP_001074534.1  zinc finger protein 707 isoform 1

    See identical proteins and their annotated locations for NP_001074534.1

    Status: VALIDATED

    Source sequence(s)
    AC116487
    Consensus CDS
    CCDS37110.1
    UniProtKB/TrEMBL
    Q8R0U9
    Related
    ENSMUSP00000105593.4, ENSMUST00000109967.10
    Conserved Domains (5) summary
    smart00349
    Location:4 → 53
    KRAB; krueppel associated box
    COG5048
    Location:123 → 302
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:229 → 249
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 29
    KRAB; KRAB box
    pfam13465
    Location:241 → 266
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001347040.2 → NP_001333969.1  zinc finger protein 707 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC116487
    Consensus CDS
    CCDS84174.1
    UniProtKB/TrEMBL
    D3Z445
    Related
    ENSMUSP00000105592.2, ENSMUST00000109966.8

  3. NM_001361464.1 → NP_001348393.1  zinc finger protein 707 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC116487
    Related
    ENSMUSP00000119705.2, ENSMUST00000147641.8
    Conserved Domains (4) summary
    smart00349
    Location:49 → 109
    KRAB; krueppel associated box
    COG5048
    Location:179 → 358
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:285 → 305
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:367 → 389
    zf-C2H2; Zinc finger, C2H2 type

  4. NM_001361465.1 → NP_001348394.1  zinc finger protein 707 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AK137962, BU920097, CJ088003
    Conserved Domains (4) summary
    smart00349
    Location:26 → 86
    KRAB; krueppel associated box
    COG5048
    Location:156 → 335
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:262 → 282
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:344 → 366
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    75840972..75847717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521341.4 → XP_006521404.1  zinc finger protein 707 isoform X1

    Conserved Domains (4) summary
    smart00349
    Location:48 → 108
    KRAB; krueppel associated box
    COG5048
    Location:178 → 357
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:284 → 304
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:366 → 388
    zf-C2H2; Zinc finger, C2H2 type
Nucleotide Protein Strain
Heading Accession and Version

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