Dera deoxyribose-phosphate aldolase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Deraprovided by RGD
Official Full Name: deoxyribose-phosphate aldolaseprovided by RGD
Primary source: RGD:1589836
See related: Ensembl:ENSRNOG00000007570 AllianceGenome:RGD:1589836
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Dera-ps1
Summary: Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process; deoxyribonucleoside catabolic process; and deoxyribonucleotide catabolic process. Predicted to be located in nucleoplasm. Orthologous to human DERA (deoxyribose-phosphate aldolase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 420.0), Liver (RPKM 242.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q44

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (172394971..172473746)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (170663689..170742469)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (171748254..171826414)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH132144 (e-PCR)
- UniSTS:215427

D4RAT69 (e-PCR)
- UniSTS:122033

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables deoxyribose-phosphate aldolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables deoxyribose-phosphate aldolase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in carbohydrate catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in deoxyribonucleoside catabolic process	ISO Inferred from Sequence Orthology more info
involved_in deoxyribonucleotide catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in deoxyribose phosphate catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: deoxyribose-phosphate aldolase

Names: 2-deoxyribose-5-phosphate aldolase homolog, pseudogene 1; deoxyribose-phosphate aldolase (putative); deoxyribose-phosphate aldolase, pseudogene 1

NP_001385935.1

EC 4.1.2.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001399006.1 → NP_001385935.1 deoxyribose-phosphate aldolase

Status: VALIDATED

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

A6IMK8

Related

ENSRNOP00000009998.5, ENSRNOT00000009998.5

Conserved Domains (1) summary

cd00959
Location:50 → 277

DeoC; 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family