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ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 694819, updated on 5-Mar-2024

Summary

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Official Symbol
ATICprovided by VGNC
Official Full Name
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolaseprovided by VGNC
Primary source
VGNC:VGNC:70172
See related
Ensembl:ENSMMUG00000012318
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ATIC in Genome Data Viewer
Location:
chromosome: 12
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (102686308..102724523)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (97287750..97324643)

Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 12 Neighboring gene uncharacterized LOC114671410 Neighboring gene small nucleolar RNA U13 Neighboring gene fibronectin 1 Neighboring gene uncharacterized LOC114671411

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables IMP cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional purine biosynthesis protein PURH
Names
bifunctional purine biosynthesis protein PURH-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041765.1 Reference Mmul_10 Primary Assembly

    Range
    102686308..102724523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002808023.3 → XP_002808069.3  bifunctional purine biosynthesis protein PURH

    UniProtKB/TrEMBL
    A0A5F7ZWN5, A0A8J8YAT9, G7N8U6, H9EQS2
    Related
    ENSMMUP00000070071.1, ENSMMUT00000084525.1
    Conserved Domains (2) summary
    PRK07106
    Location:203 → 592
    PRK07106; 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; Provisional
    cd01421
    Location:5 → 193
    IMPCH; Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates ...
Nucleotide Protein
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