U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SCN8A sodium voltage-gated channel alpha subunit 8 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 695972, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
SCN8Aprovided by VGNC
Official Full Name
sodium voltage-gated channel alpha subunit 8provided by VGNC
Primary source
VGNC:VGNC:76989
See related
Ensembl:ENSMMUG00000000415
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 11
Exon count:
28
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (51204385..51418408)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (49898075..50114166)

Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene polypeptide N-acetylgalactosaminyltransferase 6 Neighboring gene uncharacterized LOC114670847 Neighboring gene solute carrier family 4 member 8 Neighboring gene heterogeneous nuclear ribonucleoprotein A3-like Neighboring gene fidgetin like 2 Neighboring gene ankyrin repeat domain 33

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
sodium channel protein type 8 subunit alpha
Names
sodium channel, voltage gated, type VIII, alpha subunit

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041764.1 Reference Mmul_10 Primary Assembly

    Range
    51204385..51418408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028829495.1 → XP_028685328.1  sodium channel protein type 8 subunit alpha isoform X1

    UniProtKB/TrEMBL
    G7N706
    Conserved Domains (6) summary
    smart00015
    Location:1905 → 1926
    IQ; Calmodulin-binding motif
    cd13433
    Location:1476 → 1528
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1208 → 1484
    Ion_trans; Ion transport protein
    pfam06512
    Location:1002 → 1203
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:502 → 703
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1791 → 1854
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_028829497.1 → XP_028685330.1  sodium channel protein type 8 subunit alpha isoform X3

    UniProtKB/TrEMBL
    F7ADS8, G7N706
    Related
    ENSMMUP00000064417.1, ENSMMUT00000089898.1
    Conserved Domains (6) summary
    smart00015
    Location:1894 → 1915
    IQ; Calmodulin-binding motif
    cd13433
    Location:1465 → 1517
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1197 → 1473
    Ion_trans; Ion transport protein
    pfam06512
    Location:991 → 1192
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:502 → 692
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1780 → 1843
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  3. XM_028829498.1 → XP_028685331.1  sodium channel protein type 8 subunit alpha isoform X4

    UniProtKB/TrEMBL
    F7ADR2, G7N706
    Related
    ENSMMUP00000000558.4, ENSMMUT00000000607.4
    Conserved Domains (6) summary
    smart00015
    Location:1894 → 1915
    IQ; Calmodulin-binding motif
    cd13433
    Location:1465 → 1517
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1197 → 1473
    Ion_trans; Ion transport protein
    pfam06512
    Location:991 → 1192
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:502 → 692
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1780 → 1843
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  4. XM_028829499.1 → XP_028685332.1  sodium channel protein type 8 subunit alpha isoform X5

    UniProtKB/TrEMBL
    F7AD73
    Conserved Domains (6) summary
    smart00015
    Location:1853 → 1874
    IQ; Calmodulin-binding motif
    cd13433
    Location:1424 → 1476
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1481 → 1735
    Ion_trans; Ion transport protein
    pfam06512
    Location:991 → 1192
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:502 → 692
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1739 → 1802
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  5. XM_028829496.1 → XP_028685329.1  sodium channel protein type 8 subunit alpha isoform X2

    UniProtKB/TrEMBL
    G7N706
    Conserved Domains (6) summary
    smart00015
    Location:1905 → 1926
    IQ; Calmodulin-binding motif
    cd13433
    Location:1476 → 1528
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1208 → 1484
    Ion_trans; Ion transport protein
    pfam06512
    Location:1002 → 1203
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:502 → 703
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1791 → 1854
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.