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HAND2 heart and neural crest derivatives expressed 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 696881, updated on 5-Mar-2024

Summary

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Official Symbol
HAND2provided by VGNC
Official Full Name
heart and neural crest derivatives expressed 2provided by VGNC
Primary source
VGNC:VGNC:100233
See related
Ensembl:ENSMMUG00000048816
Gene type
protein coding
RefSeq status
INFERRED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
2
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (170818845..170822596, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (173701923..173705652, complement)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L5 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114678435 Neighboring gene uncharacterized LOC106998584 Neighboring gene GTP-binding nuclear protein Ran-like Neighboring gene DNA-directed RNA polymerase III subunit RPC10 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
heart- and neural crest derivatives-expressed protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193765.2 → NP_001180694.1  heart- and neural crest derivatives-expressed protein 2

    Status: INFERRED

    Source sequence(s)
    QNVO02000369
    UniProtKB/TrEMBL
    F7H124
    Related
    ENSMMUP00000034525.2, ENSMMUT00000041498.3
    Conserved Domains (1) summary
    pfam00010
    Location:69 → 120
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    170818845..170822596 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001085842.4 → XP_001085842.1  heart- and neural crest derivatives-expressed protein 2 isoform X1

    See identical proteins and their annotated locations for XP_001085842.1

    UniProtKB/TrEMBL
    A0A1D5QY03
    Conserved Domains (1) summary
    cd11471
    Location:100 → 161
    bHLH_TS_HAND2; basic helix-loop-helix (bHLH) domain found in heart- and neural crest derivatives-expressed protein 2 (HAND2) and similar proteins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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