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Eif1ad eukaryotic translation initiation factor 1A domain containing [ Mus musculus (house mouse) ]

Gene ID: 69860, updated on 11-Apr-2024

Summary

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Official Symbol
Eif1adprovided by MGI
Official Full Name
eukaryotic translation initiation factor 1A domain containingprovided by MGI
Primary source
MGI:MGI:1917110
See related
Ensembl:ENSMUSG00000024841 AllianceGenome:MGI:1917110
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Eif1ad1; 2010003J03Rik
Summary
Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in intermediate filament cytoskeleton and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; brain; genitourinary system; gut; and respiratory system. Orthologous to human EIF1AD (eukaryotic translation initiation factor 1A domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 20.2), thymus adult (RPKM 14.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
19 A; 19 4.31 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5416841..5421546)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5366813..5371518)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cation channel, sperm associated 1 Neighboring gene cystatin E/M Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5366783-5366974 Neighboring gene BAF nuclear assembly factor 1 Neighboring gene squamous cell carcinoma antigen recognized by T cells 1 Neighboring gene RIKEN cDNA D330050I16 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5389816-5390049 Neighboring gene testis specific 10 interacting protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
probable RNA-binding protein EIF1AD
Names
eukaryotic translation initiation factor 1A domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027236.2 → NP_081512.1  probable RNA-binding protein EIF1AD

    See identical proteins and their annotated locations for NP_081512.1

    Status: PROVISIONAL

    Source sequence(s)
    AC122861
    Consensus CDS
    CCDS29459.1
    UniProtKB/Swiss-Prot
    Q3THJ3, Q8K1C2, Q9D8F9
    Related
    ENSMUSP00000025759.8, ENSMUST00000025759.9
    Conserved Domains (1) summary
    cd05792
    Location:25 → 102
    S1_eIF1AD_like; eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found in a wide ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    5416841..5421546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251073.1 → XP_030106933.1  probable RNA-binding protein EIF1AD isoform X1

    UniProtKB/Swiss-Prot
    Q3THJ3, Q8K1C2, Q9D8F9
    Conserved Domains (1) summary
    cd05792
    Location:25 → 102
    S1_eIF1AD_like; eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found in a wide ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3THJ3.2 GenPept UniProtKB/Swiss-Prot:Q3THJ3

Gene LinkOut

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