TOX thymocyte selection associated high mobility group box [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: TOXprovided by VGNC
Official Full Name: thymocyte selection associated high mobility group boxprovided by VGNC
Primary source: VGNC:VGNC:79165
See related: Ensembl:ENSMMUG00000010971
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	8	NC_041761.1 (59450801..59761053, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	8	NC_027900.1 (56814457..57127005, complement)

Chromosome 8 - NC_041761.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D8S2115 (e-PCR)
- UniSTS:63514

TOX__1212 (e-PCR)
- UniSTS:468769

WI-14705 (e-PCR)
- UniSTS:22618

RH102300 (e-PCR)
- UniSTS:96634

G10593 (e-PCR)
- UniSTS:67452

RH92770 (e-PCR)
- UniSTS:92038

RH99181 (e-PCR)
- UniSTS:91274

RH11975 (e-PCR)
- UniSTS:81548

AU046597 (e-PCR)
- UniSTS:111301

WI-20692 (e-PCR)
- UniSTS:49359

RH119283 (e-PCR)
- UniSTS:133845

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chromatin DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in leukocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: thymocyte selection-associated high mobility group box protein TOX

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261489.2 → NP_001248418.1 thymocyte selection-associated high mobility group box protein TOX

See identical proteins and their annotated locations for NP_001248418.1

Status: PROVISIONAL

Source sequence(s)

JV045426

UniProtKB/TrEMBL

F7GDG8, H9F9J6, I0FM21

Related

ENSMMUP00000014382.3, ENSMMUT00000015350.4

Conserved Domains (2) summary

COG5648
Location:257 → 360

NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]

cd00084
Location:261 → 310

HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041761.1 Reference Mmul_10 Primary Assembly

Range

59450801..59761053 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028852140.1 → XP_028707973.1 thymocyte selection-associated high mobility group box protein TOX isoform X1

UniProtKB/TrEMBL

F7GDG8

Conserved Domains (2) summary

COG5648
Location:235 → 338

NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]

cd00084
Location:239 → 288

HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...