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Tspo2 translocator protein 2 [ Mus musculus (house mouse) ]

Gene ID: 70026, updated on 23-Jun-2021

Summary

Official Symbol
Tspo2provided by MGI
Official Full Name
translocator protein 2provided by MGI
Primary source
MGI:MGI:1917276
See related
Ensembl:ENSMUSG00000023995
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bzr; Bzrpl1; 2510027D20Rik
Expression
Biased expression in liver E14.5 (RPKM 59.7), liver E14 (RPKM 47.7) and 2 other tissues See more
Orthologs
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Genomic context

See Tspo2 in Genome Data Viewer
Location:
17; 17 C
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (48754970..48758592, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (48447942..48451564, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (48587760..48590826, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2 Neighboring gene predicted gene, 30283 Neighboring gene VISTA enhancer mm243 Neighboring gene unc-5 family C-terminal like Neighboring gene predicted gene, 30419

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Clone Names

  • MGC129410, MGC129411

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cholesterol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cholesterol binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in amino acid import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in enucleate erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular cholesterol transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lipid droplet organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in organelle membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
translocator protein 2
Names
benzodiazapine receptor, peripheral-like 1
peripheral-type benzodiazepine receptor-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027292.2NP_081568.1  translocator protein 2

    See identical proteins and their annotated locations for NP_081568.1

    Status: PROVISIONAL

    Source sequence(s)
    AK011003
    Consensus CDS
    CCDS28869.1
    UniProtKB/Swiss-Prot
    Q9CRZ8
    Related
    ENSMUSP00000024794.6, ENSMUST00000024794.12
    Conserved Domains (1) summary
    pfam03073
    Location:10153
    TspO_MBR; TspO/MBR family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    48754970..48758592 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317631.2XP_017173120.1  translocator protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q9CRZ8
    Conserved Domains (1) summary
    pfam03073
    Location:10153
    TspO_MBR; TspO/MBR family
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