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Ogfrl1 opioid growth factor receptor-like 1 [ Mus musculus (house mouse) ]

Gene ID: 70155, updated on 2-Apr-2024

Summary

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Official Symbol
Ogfrl1provided by MGI
Official Full Name
opioid growth factor receptor-like 1provided by MGI
Primary source
MGI:MGI:1917405
See related
Ensembl:ENSMUSG00000026158 AllianceGenome:MGI:1917405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210417C17Rik
Summary
Predicted to enable G protein-coupled opioid receptor activity. Predicted to be located in membrane. Is expressed in forebrain; ganglia; and genitourinary system. Orthologous to human OGFRL1 (opioid growth factor receptor like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 19.4), cortex adult (RPKM 16.1) and 23 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 A5; 1 9.57 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (23405505..23422282, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (23366424..23383201, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53541 Neighboring gene microRNA 30c-2 Neighboring gene STARR-seq mESC enhancer starr_00429 Neighboring gene STARR-seq mESC enhancer starr_00430 Neighboring gene STARR-seq mESC enhancer starr_00431 Neighboring gene chaperonin containing Tcp1, subunit 8 (theta) pseudogene Neighboring gene STARR-seq mESC enhancer starr_00432 Neighboring gene predicted gene, 19673 Neighboring gene STARR-seq mESC enhancer starr_00434 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Gene expression analysis of the embryonic subplate. Oeschger FM, et al. Cereb Cortex, 2012 Jun. PMID 21862448, Free PMC Article
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables opioid growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
opioid growth factor receptor-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081079.1 → NP_001074548.1  opioid growth factor receptor-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001074548.1

    Status: VALIDATED

    Source sequence(s)
    AC165368
    Consensus CDS
    CCDS35526.1
    UniProtKB/Swiss-Prot
    Q8VE52
    Related
    ENSMUSP00000027343.6, ENSMUST00000027343.6
    Conserved Domains (2) summary
    pfam05887
    Location:6 → 93
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)
    pfam04664
    Location:114 → 319
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region

  2. NM_001379082.1 → NP_001366011.1  opioid growth factor receptor-like protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC165368
    Conserved Domains (2) summary
    COG4223
    Location:322 → 433
    COG4223; Uncharacterized conserved protein [Function unknown]
    pfam04664
    Location:115 → 320
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region

  3. NM_001379083.1 → NP_001366012.1  opioid growth factor receptor-like protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC165368
    Conserved Domains (2) summary
    COG4223
    Location:250 → 361
    COG4223; Uncharacterized conserved protein [Function unknown]
    pfam04664
    Location:114 → 248
    OGFr_N; Opioid growth factor receptor (OGFr) conserved region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    23405505..23422282 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VE52.2 GenPept UniProtKB/Swiss-Prot:Q8VE52

Gene LinkOut

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