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ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702115, updated on 5-Mar-2024

Summary

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Official Symbol
ARAP2provided by VGNC
Official Full Name
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2provided by VGNC
Primary source
VGNC:VGNC:69843
See related
Ensembl:ENSMMUG00000006871
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
38
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (35202242..35379969, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (35711872..35891588, complement)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene BTB/POZ domain-containing protein 7 pseudogene Neighboring gene LIM and senescent cell antigen-like-containing domain protein 2 pseudogene Neighboring gene uncharacterized LOC106998305 Neighboring gene death domain containing 1 Neighboring gene uncharacterized LOC114678274

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    35202242..35379969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028848386.1 → XP_028704219.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q3T6
    Related
    ENSMMUP00000042698.2, ENSMMUT00000076809.2
    Conserved Domains (9) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1113 → 1292
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:483 → 575
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:587 → 674
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:892 → 1001
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13257
    Location:1014 → 1109
    PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
    cd13259
    Location:1399 → 1519
    PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
    cd17227
    Location:1301 → 1398
    RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
    cd08856
    Location:679 → 799
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2

  2. XM_028848385.1 → XP_028704218.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    F7F841, H9FPN2
    Related
    ENSMMUP00000009032.4, ENSMMUT00000009612.4
    Conserved Domains (9) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1113 → 1292
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:483 → 575
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:587 → 674
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:892 → 1001
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13257
    Location:1014 → 1109
    PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
    cd13259
    Location:1422 → 1542
    PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
    cd17227
    Location:1324 → 1421
    RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
    cd08856
    Location:679 → 799
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2

  3. XM_015138193.2 → XP_014993679.2  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    F7F841, H9FPN2
    Conserved Domains (9) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1113 → 1292
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:483 → 575
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:587 → 674
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:892 → 1001
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13257
    Location:1014 → 1109
    PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
    cd13259
    Location:1422 → 1542
    PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
    cd17227
    Location:1324 → 1421
    RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
    cd08856
    Location:679 → 799
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2

  4. XM_028848383.1 → XP_028704216.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    F7F841, H9FPN2
    Conserved Domains (9) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1113 → 1292
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:483 → 575
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:587 → 674
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:892 → 1001
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13257
    Location:1014 → 1109
    PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
    cd13259
    Location:1422 → 1542
    PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
    cd17227
    Location:1324 → 1421
    RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
    cd08856
    Location:679 → 799
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2

  5. XM_028848384.1 → XP_028704217.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    F7F841, H9FPN2
    Conserved Domains (9) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1113 → 1292
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:483 → 575
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:587 → 674
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:892 → 1001
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13257
    Location:1014 → 1109
    PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
    cd13259
    Location:1422 → 1542
    PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
    cd17227
    Location:1324 → 1421
    RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
    cd08856
    Location:679 → 799
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2

  6. XM_028848387.1 → XP_028704220.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    H9FPN2
    Conserved Domains (9) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1113 → 1292
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:483 → 575
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:587 → 674
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:892 → 1001
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13257
    Location:1014 → 1109
    PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
    cd17227
    Location:1324 → 1421
    RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
    cd08856
    Location:679 → 799
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2
    cl17171
    Location:1422 → 1474
    PH-like; Pleckstrin homology-like domain

RNA

  1. XR_003729594.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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