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Nars asparaginyl-tRNA synthetase [ Mus musculus (house mouse) ]

Gene ID: 70223, updated on 3-Aug-2021

Summary

Official Symbol
Narsprovided by MGI
Official Full Name
asparaginyl-tRNA synthetaseprovided by MGI
Primary source
MGI:MGI:1917473
See related
Ensembl:ENSMUSG00000024587
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ASNRS; NARS1; C78150; AA960128; 3010001M15Rik
Expression
Ubiquitous expression in liver E14 (RPKM 51.7), placenta adult (RPKM 44.5) and 28 other tissues See more
Orthologs
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Genomic context

See Nars in Genome Data Viewer
Location:
18; 18 E1
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (64632726..64649586, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (64499655..64516515, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (64659301..64676211, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 3 Neighboring gene ferrochelatase Neighboring gene ATPase, class I, type 8B, member 1 Neighboring gene predicted gene 6978 Neighboring gene predicted gene, 23016

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables CCR3 chemokine receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables asparagine-tRNA ligase activity ISO
Inferred from Sequence Orthology
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein dimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in asparaginyl-tRNA aminoacylation ISO
Inferred from Sequence Orthology
more info
 
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in cerebral cortex development ISO
Inferred from Sequence Orthology
more info
 
involved_in tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 

General protein information

Preferred Names
asparagine--tRNA ligase, cytoplasmic
Names
asparaginyl-tRNA synthetase 1
asparaginyl-tRNA synthetase, cytoplasmic
NP_001136422.2
NP_001363950.1
NP_001363951.1
NP_001363952.1
NP_081626.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142950.2NP_001136422.2  asparagine--tRNA ligase, cytoplasmic isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC102268
    Consensus CDS
    CCDS50308.1
    Related
    ENSMUSP00000157402.2, ENSMUST00000237400.2
    Conserved Domains (1) summary
    COG0017
    Location:125548
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
  2. NM_001377021.1NP_001363950.1  asparagine--tRNA ligase, cytoplasmic isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC102268
    Conserved Domains (1) summary
    COG0017
    Location:126549
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
  3. NM_001377022.1NP_001363951.1  asparagine--tRNA ligase, cytoplasmic isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC102268
    Conserved Domains (1) summary
    COG0017
    Location:125546
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
  4. NM_001377023.1NP_001363952.1  asparagine--tRNA ligase, cytoplasmic isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC102268
    Related
    ENSMUSP00000158278.2, ENSMUST00000237351.2
    Conserved Domains (1) summary
    COG0017
    Location:95518
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
  5. NM_027350.4NP_081626.3  asparagine--tRNA ligase, cytoplasmic isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC102268
    Consensus CDS
    CCDS89261.1
    Related
    ENSMUSP00000025483.11, ENSMUST00000025483.11
    Conserved Domains (1) summary
    COG0017
    Location:124547
    AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    64632726..64649586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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