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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702553, updated on 5-Mar-2024

Summary

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Official Symbol
HMGCS1provided by VGNC
Official Full Name
3-hydroxy-3-methylglutaryl-CoA synthase 1provided by VGNC
Primary source
VGNC:VGNC:73485
Locus tag
EGK_21191
See related
Ensembl:ENSMMUG00000001226
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (43297245..43321487, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (44074478..44099004, complement)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene spermine synthase pseudogene Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene tubulin alpha-1C chain pseudogene Neighboring gene 60S acidic ribosomal protein P1 pseudogene Neighboring gene uncharacterized LOC106998744 Neighboring gene C-C motif chemokine ligand 28

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic
Names
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
NP_001247798.1
XP_014995459.1
XP_014995460.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001260869.1 → NP_001247798.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for NP_001247798.1

    Status: PROVISIONAL

    Source sequence(s)
    JV045478
    UniProtKB/TrEMBL
    F7HQ90, G8F1C3, H9ETD6
    Related
    ENSMMUP00000034768.1, ENSMMUT00000041755.3
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    43297245..43321487 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015139973.2 → XP_014995459.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    F7HQ90, G8F1C3, H9ETD6
    Related
    ENSMMUP00000062864.1, ENSMMUT00000097092.1
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_015139974.2 → XP_014995460.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    F7HQ90, G8F1C3, H9ETD6
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
Heading Accession and Version

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