BLM BLM RecQ like helicase [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: BLMprovided by VGNC
Official Full Name: BLM RecQ like helicaseprovided by VGNC
Primary source: VGNC:VGNC:70254
See related: Ensembl:ENSMMUG00000019526
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	7	NC_041760.1 (69568526..69677147)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	7	NC_027899.1 (68831506..68939965)

Chromosome 7 - NC_041760.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

MARC_26779-26780:1034181609:3 (e-PCR)
- UniSTS:269074

A008V47 (e-PCR)
- UniSTS:59667

RH18053 (e-PCR)
- UniSTS:54340

NoName (e-PCR)
- UniSTS:489805

STS-T99721 (e-PCR)
- UniSTS:80808

D15S1129 (e-PCR)
- UniSTS:154550

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3'-5' DNA helicase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables four-way junction helicase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in DNA unwinding involved in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in G-quadruplex DNA unwinding	IEA Inferred from Electronic Annotation more info	PubMed
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in telomere maintenance	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: Bloom syndrome protein

Names: Bloom syndrome RecQ like helicase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041760.1 Reference Mmul_10 Primary Assembly

Range

69568526..69677147

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001097543.4 → XP_001097543.2 Bloom syndrome protein isoform X1

UniProtKB/TrEMBL

F7CS38, G7MVY7

Related

ENSMMUP00000025651.4, ENSMMUT00000027428.4

Conserved Domains (5) summary

smart00341
Location:1212 → 1291

HRDC; Helicase and RNase D C-terminal

TIGR00614
Location:656 → 1142

recQ_fam; ATP-dependent DNA helicase, RecQ family

pfam08072
Location:371 → 410

BDHCT; BDHCT (NUC031) domain

pfam16202
Location:1 → 365

BLM_N; N-terminal region of Bloom syndrome protein

pfam16204
Location:424 → 646

BDHCT_assoc; BDHCT-box associated domain on Bloom syndrome protein
XM_015143029.2 → XP_014998515.2 Bloom syndrome protein isoform X2

UniProtKB/TrEMBL

G7MVY7

Conserved Domains (5) summary

TIGR00614
Location:656 → 1142

recQ_fam; ATP-dependent DNA helicase, RecQ family

pfam08072
Location:371 → 410

BDHCT; BDHCT (NUC031) domain

pfam16202
Location:1 → 365

BLM_N; N-terminal region of Bloom syndrome protein

pfam16204
Location:424 → 646

BDHCT_assoc; BDHCT-box associated domain on Bloom syndrome protein

cl02578
Location:1212 → 1249

HRDC; HRDC domain
XM_028852012.1 → XP_028707845.1 Bloom syndrome protein isoform X1

UniProtKB/TrEMBL

F7CS38, G7MVY7

Conserved Domains (5) summary

smart00341
Location:1212 → 1291

HRDC; Helicase and RNase D C-terminal

TIGR00614
Location:656 → 1142

recQ_fam; ATP-dependent DNA helicase, RecQ family

pfam08072
Location:371 → 410

BDHCT; BDHCT (NUC031) domain

pfam16202
Location:1 → 365

BLM_N; N-terminal region of Bloom syndrome protein

pfam16204
Location:424 → 646

BDHCT_assoc; BDHCT-box associated domain on Bloom syndrome protein
XM_015143030.2 → XP_014998516.2 Bloom syndrome protein isoform X3

Conserved Domains (4) summary

smart00341
Location:838 → 917

HRDC; Helicase and RNase D C-terminal

TIGR00614
Location:282 → 768

recQ_fam; ATP-dependent DNA helicase, RecQ family

pfam08072
Location:1 → 36

BDHCT; BDHCT (NUC031) domain

pfam16204
Location:50 → 272

BDHCT_assoc; BDHCT-box associated domain on Bloom syndrome protein