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PHF8 PHD finger protein 8 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703633, updated on 5-Mar-2024

Summary

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Official Symbol
PHF8provided by VGNC
Official Full Name
PHD finger protein 8provided by VGNC
Primary source
VGNC:VGNC:75836
See related
Ensembl:ENSMMUG00000008751
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PHF8 in Genome Data Viewer
Location:
chromosome: X
Exon count:
24
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (53664032..53772630, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (53353565..53461477, complement)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene 39S ribosomal protein L32, mitochondrial pseudogene Neighboring gene 28S ribosomal protein S18c, mitochondrial pseudogene Neighboring gene 40S ribosomal protein S29 pseudogene Neighboring gene family with sequence similarity 120 member C Neighboring gene WNK lysine deficient protein kinase 3 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone demethylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone lysine demethylase PHF8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    53664032..53772630 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015127505.2 → XP_014982991.1  histone lysine demethylase PHF8 isoform X3

    UniProtKB/TrEMBL
    H9FRR4
    Conserved Domains (3) summary
    smart00558
    Location:235 → 298
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:42 → 93
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    cl21464
    Location:270 → 370
    cupin_like; Conserved domain found in cupin and related proteins

  2. XM_015127501.2 → XP_014982987.1  histone lysine demethylase PHF8 isoform X1

    UniProtKB/TrEMBL
    G7NRH7
    Related
    ENSMMUP00000011477.4, ENSMMUT00000012236.4
    Conserved Domains (3) summary
    smart00558
    Location:235 → 298
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:42 → 93
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    cl21464
    Location:270 → 370
    cupin_like; Conserved domain found in cupin and related proteins

  3. XM_015127504.2 → XP_014982990.1  histone lysine demethylase PHF8 isoform X2

    UniProtKB/TrEMBL
    F7DQX0, H9FRR4
    Related
    ENSMMUP00000011475.3, ENSMMUT00000012234.4
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain
    cl40423
    Location:234 → 334
    cupin_RmlC-like; RmlC-like cupin superfamily

  4. XM_015127502.2 → XP_014982988.1  histone lysine demethylase PHF8 isoform X2

    UniProtKB/TrEMBL
    F7DQX0, H9FRR4
    Related
    ENSMMUP00000071060.1, ENSMMUT00000093471.1
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain
    cl40423
    Location:234 → 334
    cupin_RmlC-like; RmlC-like cupin superfamily

  5. XM_015127506.2 → XP_014982992.1  histone lysine demethylase PHF8 isoform X4

    UniProtKB/TrEMBL
    H9FRR4
    Related
    ENSMMUP00000079668.1, ENSMMUT00000082202.1
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam02373
    Location:234 → 334
    JmjC; JmjC domain, hydroxylase
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain
Nucleotide Protein
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