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Taf15 TATA-box binding protein associated factor 15 [ Mus musculus (house mouse) ]

Gene ID: 70439, updated on 23-Jun-2021

Summary

Official Symbol
Taf15provided by MGI
Official Full Name
TATA-box binding protein associated factor 15provided by MGI
Primary source
MGI:MGI:1917689
See related
Ensembl:ENSMUSG00000020680
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Taf; 68kD; TAFI; 68kDa; Taf2n; TAFII68; 2610111C21Rik
Expression
Biased expression in CNS E11.5 (RPKM 81.2), CNS E14 (RPKM 33.7) and 12 other tissues See more
Orthologs
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Genomic context

See Taf15 in Genome Data Viewer
Location:
11; 11 C
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83363897..83397569)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83473073..83506743)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (83286610..83320242)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene growth arrest-specific 2 like 2 Neighboring gene RIKEN cDNA 1700020L24 gene Neighboring gene matrix metallopeptidase 28 (epilysin) Neighboring gene predicted gene, 32650 Neighboring gene HEAT repeat containing 9 Neighboring gene predicted gene, 23247 Neighboring gene chemokine (C-C motif) ligand 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within gene expression IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within mRNA stabilization ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
TATA-binding protein-associated factor 2N
Names
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA binding protein 56)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027427.3NP_081703.1  TATA-binding protein-associated factor 2N

    See identical proteins and their annotated locations for NP_081703.1

    Status: VALIDATED

    Source sequence(s)
    AK051568, AL596122
    Consensus CDS
    CCDS25168.1
    UniProtKB/TrEMBL
    Q8BQ46
    Related
    ENSMUSP00000021018.5, ENSMUST00000021018.11
    Conserved Domains (4) summary
    COG0724
    Location:221317
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12535
    Location:230315
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00029
    Location:356377
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:352382
    zf-RanBP; Zn-finger in Ran binding protein and others

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    83363897..83397569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246301.2XP_030102161.1  TATA-binding protein-associated factor 2N isoform X1

    Conserved Domains (5) summary
    PTZ00110
    Location:469
    PTZ00110; helicase; Provisional
    cd12535
    Location:197282
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    TIGR01622
    Location:106280
    SF-CC1; splicing factor, CC1-like family
    sd00029
    Location:323344
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:320349
    zf-RanBP; Zn-finger in Ran binding protein and others
  2. XM_030246302.2XP_030102162.1  TATA-binding protein-associated factor 2N isoform X2

    Conserved Domains (5) summary
    PTZ00110
    Location:469
    PTZ00110; helicase; Provisional
    cd12535
    Location:178263
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00029
    Location:304325
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:301330
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam12273
    Location:102153
    RCR; Chitin synthesis regulation, resistance to Congo red
  3. XM_030246304.1XP_030102164.1  TATA-binding protein-associated factor 2N isoform X3

    Related
    ENSMUSP00000119836.2, ENSMUST00000133170.2
    Conserved Domains (3) summary
    cd12535
    Location:35120
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00029
    Location:161182
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:158187
    zf-RanBP; Zn-finger in Ran binding protein and others
  4. XM_030246305.2XP_030102165.1  TATA-binding protein-associated factor 2N isoform X4

    Conserved Domains (3) summary
    sd00025
    Location:89110
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:85115
    zf-RanBP; Zn-finger in Ran binding protein and others
    cl17169
    Location:148
    RRM_SF; RNA recognition motif (RRM) superfamily
  5. XM_036156982.1XP_036012875.1  TATA-binding protein-associated factor 2N isoform X4

    Conserved Domains (3) summary
    sd00025
    Location:89110
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:85115
    zf-RanBP; Zn-finger in Ran binding protein and others
    cl17169
    Location:148
    RRM_SF; RNA recognition motif (RRM) superfamily
  6. XM_036156984.1XP_036012877.1  TATA-binding protein-associated factor 2N isoform X4

    Conserved Domains (3) summary
    sd00025
    Location:89110
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:85115
    zf-RanBP; Zn-finger in Ran binding protein and others
    cl17169
    Location:148
    RRM_SF; RNA recognition motif (RRM) superfamily
  7. XM_036156983.1XP_036012876.1  TATA-binding protein-associated factor 2N isoform X4

    Conserved Domains (3) summary
    sd00025
    Location:89110
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:85115
    zf-RanBP; Zn-finger in Ran binding protein and others
    cl17169
    Location:148
    RRM_SF; RNA recognition motif (RRM) superfamily
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