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Bbx bobby sox HMG box containing [ Mus musculus (house mouse) ]

Gene ID: 70508, updated on 11-Apr-2024

Summary

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Official Symbol
Bbxprovided by MGI
Official Full Name
bobby sox HMG box containingprovided by MGI
Primary source
MGI:MGI:1917758
See related
Ensembl:ENSMUSG00000022641 AllianceGenome:MGI:1917758
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5530401J07Rik; 5730403O13Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within bone development. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human BBX (BBX high mobility group box domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 16.6), testis adult (RPKM 10.8) and 23 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 B5; 16 31.35 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (50012207..50252829, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (50191844..50432466, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4827 Neighboring gene predicted gene, 32101 Neighboring gene STARR-seq mESC enhancer starr_40979 Neighboring gene STARR-seq mESC enhancer starr_40980 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_40982 Neighboring gene STARR-seq mESC enhancer starr_40984 Neighboring gene STARR-seq mESC enhancer starr_40987 Neighboring gene STARR-positive B cell enhancer mm9_chr16:50432445-50432746 Neighboring gene STARR-seq mESC enhancer starr_40989 Neighboring gene STARR-seq mESC enhancer starr_40990 Neighboring gene predicted gene, 32231 Neighboring gene predicted gene, 41459

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex. Sánchez-Díaz A, et al. Curr Genet, 2001 Sep. PMID 11680820
  2. Nuclear factor one X regulates Bobby sox during development of the mouse forebrain. Dixon C, et al. Cell Mol Neurobiol, 2013 Oct. PMID 23852417
  3. Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic. Chen T, et al. Dev Genes Evol, 2014 Dec. PMID 25079045
  4. A Leishmania major response locus identified by interval-specific congenic mapping of a T helper type 2 cell bias-controlling quantitative trait locus. Baguet A, et al. J Exp Med, 2004 Dec 20. PMID 15596523, Free PMC Article
  5. Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. Bassett JH, et al. PLoS Genet, 2012. PMID 22876197, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Immunohistochemistry analysis in mouse brain revealed that BBX was weakly expressed in the cerebellum and highly expressed in the cortex and hippocampus.
    Title: Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic.
  2. Bbx is a downstream target of NFIX during development of the forebrain.
    Title: Nuclear factor one X regulates Bobby sox during development of the mouse forebrain.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within bone development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
HMG box transcription factor BBX
Names
HMG box-containing protein 2
bobby sox homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347240.1 → NP_001334169.1  HMG box transcription factor BBX isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154781, AK029747, CT571273
    Consensus CDS
    CCDS84241.1
    UniProtKB/Swiss-Prot
    Q8VBW5
    Related
    ENSMUSP00000086826.4, ENSMUST00000089404.10
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  2. NM_027444.3 → NP_081720.2  HMG box transcription factor BBX isoform 1

    See identical proteins and their annotated locations for NP_081720.2

    Status: VALIDATED

    Source sequence(s)
    AC109627, AC113067, AC154781, CT571273
    Consensus CDS
    CCDS37354.1
    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Related
    ENSMUSP00000119238.2, ENSMUST00000138166.8
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    50012207..50252829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249277.2 → XP_030105137.1  HMG box transcription factor BBX isoform X3

    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  2. XM_011246009.3 → XP_011244311.1  HMG box transcription factor BBX isoform X5

    See identical proteins and their annotated locations for XP_011244311.1

    UniProtKB/Swiss-Prot
    Q8VBW5
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  3. XM_006522546.3 → XP_006522609.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522609.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  4. XM_017317130.3 → XP_017172619.1  HMG box transcription factor BBX isoform X3

    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  5. XM_030249281.2 → XP_030105141.1  HMG box transcription factor BBX isoform X6

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 295
    DUF2028; Domain of unknown function (DUF2028)

  6. XM_011246008.4 → XP_011244310.1  HMG box transcription factor BBX isoform X3

    See identical proteins and their annotated locations for XP_011244310.1

    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Related
    ENSMUSP00000110132.2, ENSMUST00000114488.8
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  7. XM_006522549.5 → XP_006522612.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522612.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  8. XM_030249275.2 → XP_030105135.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  9. XM_006522547.5 → XP_006522610.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522610.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  10. XM_036160122.1 → XP_036016015.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 295
    DUF2028; Domain of unknown function (DUF2028)

  11. XM_036160123.1 → XP_036016016.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 295
    DUF2028; Domain of unknown function (DUF2028)

  12. XM_036160118.1 → XP_036016011.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  13. XM_006522544.5 → XP_006522607.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522607.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  14. XM_006522545.5 → XP_006522608.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522608.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  15. XM_006522554.5 → XP_006522617.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522617.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  16. XM_036160120.1 → XP_036016013.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  17. XM_011246006.4 → XP_011244308.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_011244308.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  18. XM_036160126.1 → XP_036016019.1  HMG box transcription factor BBX isoform X7

    Related
    ENSMUSP00000066384.7, ENSMUST00000066037.13
    Conserved Domains (2) summary
    cd01388
    Location:54 → 112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152 → 257
    DUF2028; Domain of unknown function (DUF2028)

  19. XM_030249278.2 → XP_030105138.1  HMG box transcription factor BBX isoform X4

    Conserved Domains (2) summary
    cd01388
    Location:54 → 112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152 → 284
    DUF2028; Domain of unknown function (DUF2028)

  20. XM_011246005.4 → XP_011244307.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_011244307.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  21. XM_006522543.5 → XP_006522606.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522606.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  22. XM_006522553.5 → XP_006522616.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522616.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  23. XM_036160121.1 → XP_036016014.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 295
    DUF2028; Domain of unknown function (DUF2028)

  24. XM_006522561.5 → XP_006522624.1  HMG box transcription factor BBX isoform X4

    See identical proteins and their annotated locations for XP_006522624.1

    Conserved Domains (2) summary
    cd01388
    Location:54 → 112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152 → 284
    DUF2028; Domain of unknown function (DUF2028)

  25. XM_006522560.5 → XP_006522623.1  HMG box transcription factor BBX isoform X4

    See identical proteins and their annotated locations for XP_006522623.1

    Conserved Domains (2) summary
    cd01388
    Location:54 → 112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152 → 284
    DUF2028; Domain of unknown function (DUF2028)

  26. XM_011246007.4 → XP_011244309.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 295
    DUF2028; Domain of unknown function (DUF2028)

  27. XM_006522555.5 → XP_006522618.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522618.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  28. XM_030249279.2 → XP_030105139.1  HMG box transcription factor BBX isoform X4

    Conserved Domains (2) summary
    cd01388
    Location:54 → 112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152 → 284
    DUF2028; Domain of unknown function (DUF2028)

  29. XM_036160116.1 → XP_036016009.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  30. XM_030249274.2 → XP_030105134.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  31. XM_036160117.1 → XP_036016010.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  32. XM_006522548.5 → XP_006522611.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522611.1

    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)

  33. XM_036160125.1 → XP_036016018.1  HMG box transcription factor BBX isoform X5

    Related
    ENSMUSP00000086821.5, ENSMUST00000089399.11
    Conserved Domains (2) summary
    cd01388
    Location:79 → 150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190 → 322
    DUF2028; Domain of unknown function (DUF2028)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VBW5.2 GenPept UniProtKB/Swiss-Prot:Q8VBW5

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