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Zdhhc2 zinc finger, DHHC domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 70546, updated on 26-Jun-2021

Summary

Official Symbol
Zdhhc2provided by MGI
Official Full Name
zinc finger, DHHC domain containing 2provided by MGI
Primary source
MGI:MGI:1923452
See related
Ensembl:ENSMUSG00000039470
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DHHC-2; 5730415P04Rik; 6430583A19Rik
Expression
Broad expression in CNS E18 (RPKM 7.5), cortex adult (RPKM 6.3) and 21 other tissues See more
Orthologs
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Genomic context

See Zdhhc2 in Genome Data Viewer
Location:
8; 8 A4
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (40876526..40946178)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (40423485..40489592)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (41509169..41570196)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 20 Neighboring gene microRNA 7666 Neighboring gene mitochondrial calcium uptake family, member 3 Neighboring gene CCR4-NOT transcription complex, subunit 7 Neighboring gene vacuolar protein sorting 37A Neighboring gene myotubularin related protein 7 Neighboring gene a disintegrin and metallopeptidase domain 24 (testase 1)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC156396

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in peptidyl-L-cysteine S-palmitoylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptidyl-L-cysteine S-palmitoylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-L-cysteine S-palmitoylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-L-cysteine S-palmitoylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of AMPA glutamate receptor clustering ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of endosome to plasma membrane protein transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of long-term synaptic potentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein palmitoylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein palmitoylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of neuronal synaptic plasticity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in synaptic vesicle maturation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic recycling endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in recycling endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
palmitoyltransferase ZDHHC2
Names
acyltransferase ZDHHC2
zinc finger DHHC domain-containing protein 2
NP_001344178.1
NP_848482.1
XP_006509548.1
XP_036010172.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357249.1NP_001344178.1  palmitoyltransferase ZDHHC2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC118012
    Conserved Domains (1) summary
    pfam01529
    Location:6127
    DHHC; DHHC palmitoyltransferase
  2. NM_178395.4NP_848482.1  palmitoyltransferase ZDHHC2 isoform 1

    See identical proteins and their annotated locations for NP_848482.1

    Status: VALIDATED

    Source sequence(s)
    AK017566, AK030662, BE989599
    Consensus CDS
    CCDS22252.1
    UniProtKB/Swiss-Prot
    P59267
    Related
    ENSMUSP00000041727.5, ENSMUST00000049389.11
    Conserved Domains (1) summary
    pfam01529
    Location:126247
    DHHC; DHHC palmitoyltransferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    40876526..40946178
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509485.5XP_006509548.1  palmitoyltransferase ZDHHC2 isoform X1

    See identical proteins and their annotated locations for XP_006509548.1

    UniProtKB/Swiss-Prot
    P59267
    Conserved Domains (1) summary
    pfam01529
    Location:126247
    DHHC; DHHC palmitoyltransferase
  2. XM_036154279.1XP_036010172.1  palmitoyltransferase ZDHHC2 isoform X2

    Conserved Domains (1) summary
    pfam01529
    Location:6127
    DHHC; DHHC palmitoyltransferase
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