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FGF1 fibroblast growth factor 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705970, updated on 8-Oct-2019

Summary

Gene symbol
FGF1
Gene description
fibroblast growth factor 1
Locus tag
EGK_16969
See related
Ensembl:ENSMMUG00000057828
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs

Genomic context

See FGF1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
10
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (139998490..140109214, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (140408741..140482458, complement) , (140400331..140403615, complement)
Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 6 NC_007863.1 (139022246..139129783, complement)

Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998975 Neighboring gene sprouty RTK signaling antagonist 4 Neighboring gene small nucleolar RNA SNORA36 family Neighboring gene Rho GTPase activating protein 26 Neighboring gene uncharacterized LOC106998979 Neighboring gene nuclear receptor subfamily 3 group C member 1 Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Breast cancer, organism-specific biosystem (from KEGG)
    Breast cancer, organism-specific biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...
  • Breast cancer, conserved biosystem (from KEGG)
    Breast cancer, conserved biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...
  • Hippo signaling pathway, organism-specific biosystem (from KEGG)
    Hippo signaling pathway, organism-specific biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
  • Hippo signaling pathway, conserved biosystem (from KEGG)
    Hippo signaling pathway, conserved biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
  • MAPK signaling pathway, organism-specific biosystem (from KEGG)
    MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • MAPK signaling pathway, conserved biosystem (from KEGG)
    MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • Melanoma, organism-specific biosystem (from KEGG)
    Melanoma, organism-specific biosystemMelanoma is a form of skin cancer that has a poor prognosis and which is on the rise in Western populations. Melanoma arises from the malignant transformation of pigment-producing cells, melanocytes...
  • Melanoma, conserved biosystem (from KEGG)
    Melanoma, conserved biosystemMelanoma is a form of skin cancer that has a poor prognosis and which is on the rise in Western populations. Melanoma arises from the malignant transformation of pigment-producing cells, melanocytes...
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
    Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Rap1 signaling pathway, conserved biosystem (from KEGG)
    Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
  • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
    Regulation of actin cytoskeleton, organism-specific biosystem
    Regulation of actin cytoskeleton
  • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
    Regulation of actin cytoskeleton, conserved biosystem
    Regulation of actin cytoskeleton

General gene information

Markers

Homology

General protein information

Preferred Names
fibroblast growth factor 1
Names
heparin-binding growth factor 1 isoform 1 proprotein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266029.1NP_001252958.1  fibroblast growth factor 1

    See identical proteins and their annotated locations for NP_001252958.1

    Status: PROVISIONAL

    Source sequence(s)
    JU333434
    UniProtKB/TrEMBL
    F7E243
    Related
    ENSMMUP00000063304.1, ENSMMUT00000092516.1
    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041759.1 Reference Mmul_10 Primary Assembly

    Range
    139998490..140109214 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028849199.1XP_028705032.1  fibroblast growth factor 1 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
  2. XM_028849200.1XP_028705033.1  fibroblast growth factor 1 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
  3. XM_028849197.1XP_028705030.1  fibroblast growth factor 1 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
  4. XM_028849207.1XP_028705040.1  fibroblast growth factor 1 isoform X3

    Conserved Domains (1) summary
    cl00060
    Location:2557
    FGF; Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate ...
  5. XM_028849204.1XP_028705037.1  fibroblast growth factor 1 isoform X2

    Conserved Domains (1) summary
    pfam00167
    Location:25147
    FGF; Fibroblast growth factor
  6. XM_028849201.1XP_028705034.1  fibroblast growth factor 1 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
  7. XM_028849198.1XP_028705031.1  fibroblast growth factor 1 isoform X1

    Related
    ENSMMUP00000071478.1, ENSMMUT00000098342.1
    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
  8. XM_028849208.1XP_028705041.1  fibroblast growth factor 1 isoform X3

    Conserved Domains (1) summary
    cl00060
    Location:2557
    FGF; Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate ...
  9. XM_028849205.1XP_028705038.1  fibroblast growth factor 1 isoform X2

    Conserved Domains (1) summary
    pfam00167
    Location:25147
    FGF; Fibroblast growth factor
  10. XM_028849206.1XP_028705039.1  fibroblast growth factor 1 isoform X2

    Related
    ENSMMUP00000079302.1, ENSMMUT00000081214.1
    Conserved Domains (1) summary
    pfam00167
    Location:25147
    FGF; Fibroblast growth factor
  11. XM_028849202.1XP_028705035.1  fibroblast growth factor 1 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
  12. XM_028849203.1XP_028705036.1  fibroblast growth factor 1 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:25148
    FGF; Fibroblast growth factor
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