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CYP3A43 cytochrome P450 family 3 subfamily A member 43 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 709770, updated on 5-Mar-2024

Summary

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Official Symbol
CYP3A43provided by VGNC
Official Full Name
cytochrome P450 family 3 subfamily A member 43provided by VGNC
Primary source
VGNC:VGNC:103656
See related
Ensembl:ENSMMUG00000022490
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human all
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Genomic context

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Location:
chromosome: 3
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (41999570..42044248)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (125336301..125377469)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 3A7-like Neighboring gene cytochrome P450 3A64 Neighboring gene olfactory receptor 2AE1 Neighboring gene tripartite motif containing 4 Neighboring gene uncharacterized LOC106997574

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CYP3 phylogenomics: evidence for positive selection of CYP3A4 and CYP3A7. Qiu H, et al. Pharmacogenet Genomics, 2008 Jan. PMID 18216722

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estrogen 16-alpha-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables testosterone 6-beta-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in oxidative demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in steroid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytochrome P450 3A43
Names
cytochrome P450, family 3, subfamily A, polypeptide 43
NP_001121102.1
XP_028700814.1
XP_028700815.1
XP_028700816.1
XP_028700817.1
XP_028700818.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127630.1 → NP_001121102.1  cytochrome P450 3A43 precursor

    See identical proteins and their annotated locations for NP_001121102.1

    Status: PROVISIONAL

    Source sequence(s)
    EF589792
    UniProtKB/TrEMBL
    B1NL88, F7GFZ4
    Related
    ENSMMUP00000029936.4, ENSMMUT00000031994.4
    Conserved Domains (1) summary
    pfam00067
    Location:22 → 444
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    41999570..42044248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028844985.1 → XP_028700818.1  cytochrome P450 3A43 isoform X5

    UniProtKB/TrEMBL
    F7GFZ4
    Conserved Domains (1) summary
    pfam00067
    Location:1 → 423
    p450; Cytochrome P450

  2. XM_028844983.1 → XP_028700816.1  cytochrome P450 3A43 isoform X3

    UniProtKB/TrEMBL
    B1NL87, F7A3T2
    Related
    ENSMMUP00000029597.3, ENSMMUT00000031637.3
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 428
    p450; Cytochrome P450

  3. XM_028844982.1 → XP_028700815.1  cytochrome P450 3A43 isoform X2

    UniProtKB/TrEMBL
    F7GFZ4
    Conserved Domains (1) summary
    pfam00067
    Location:15 → 451
    p450; Cytochrome P450

  4. XM_028844981.1 → XP_028700814.1  cytochrome P450 3A43 isoform X1

    UniProtKB/TrEMBL
    F7A3W6
    Related
    ENSMMUP00000029594.4, ENSMMUT00000031634.4
    Conserved Domains (1) summary
    pfam00067
    Location:39 → 493
    p450; Cytochrome P450

  5. XM_028844984.1 → XP_028700817.1  cytochrome P450 3A43 isoform X4

    UniProtKB/TrEMBL
    F7GFZ4
    Conserved Domains (1) summary
    pfam00067
    Location:1 → 383
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version

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