PPP2CA protein phosphatase 2 catalytic subunit alpha [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: PPP2CA
Gene description: protein phosphatase 2 catalytic subunit alpha
See related: Ensembl:ENSMMUG00000013047
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	6	NC_041759.1 (131634048..131666196, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	6	NC_027898.1 (131885659..131915936, complement)

Chromosome 6 - NC_041759.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Ppp2ca (e-PCR), detects polymorphism
- UniSTS:526870

Ppp2ca (e-PCR), detects polymorphism
- UniSTS:526871

PMC22838P1 (e-PCR)
- UniSTS:272153

WI-18935 (e-PCR)
- UniSTS:22638

PPP2CA_3845 (e-PCR)
- UniSTS:462448

RH68282 (e-PCR)
- UniSTS:71536

D5S2601 (e-PCR)
- UniSTS:59548

PPP2CA (e-PCR)
- UniSTS:278947

D5S2786 (e-PCR)
- UniSTS:473854

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-serine dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041759.1 Reference Mmul_10 Primary Assembly

Range

131634048..131666196 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028849730.1 → XP_028705563.1 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform X3

Conserved Domains (1) summary

cl13995
Location:9 → 223

MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
XM_028849729.1 → XP_028705562.1 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform X2

UniProtKB/TrEMBL

G7MZ21

Conserved Domains (1) summary

cd07415
Location:1 → 228

MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain
XM_015140928.2 → XP_014996414.1 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform X1

UniProtKB/TrEMBL

F7H808, G7MZ21

Related

ENSMMUP00000017139.2, ENSMMUT00000018308.4

Conserved Domains (1) summary

cd07415
Location:9 → 293

MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain