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Scara5 scavenger receptor class A, member 5 [ Mus musculus (house mouse) ]

Gene ID: 71145, updated on 6-May-2021

Summary

Official Symbol
Scara5provided by MGI
Official Full Name
scavenger receptor class A, member 5provided by MGI
Primary source
MGI:MGI:1918395
See related
Ensembl:ENSMUSG00000022032
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tesr; AV278087; 4932433F15Rik; 4933425F03Rik
Expression
Biased expression in bladder adult (RPKM 37.1), mammary gland adult (RPKM 14.4) and 10 other tissues See more
Orthologs
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Genomic context

See Scara5 in Genome Data Viewer
Location:
14; 14 D1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (65903852..66002275)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65666403..65764826)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66285240..66383663)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene nuclear GTPase, germinal center associated Neighboring gene predicted gene, 30245 Neighboring gene uncharacterized LOC118568159 Neighboring gene PDZ binding kinase Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ferritin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables scavenger receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular iron ion homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within cellular response to heat IDA
Inferred from Direct Assay
more info
PubMed 
involved_in endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in iron ion transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein homotrimerization IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in endocytic vesicle membrane TAS
Traceable Author Statement
more info
 
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
scavenger receptor class A member 5
Names
scavenger receptor class A, member 5 (putative)
testis expressed scavenger receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168318.1NP_001161790.1  scavenger receptor class A member 5 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two 3' exons but has an alternate 3' exon, as compared to variant 1. The resulting isoform (2) is shorter and has a different C-terminus, as compared to isoform 1.
    Source sequence(s)
    AK016543, AK033154, BY791906
    Consensus CDS
    CCDS49523.1
    UniProtKB/Swiss-Prot
    Q8K299
    Related
    ENSMUSP00000063391.7, ENSMUST00000069226.7
    Conserved Domains (2) summary
    pfam01391
    Location:306373
    Collagen; Collagen triple helix repeat (20 copies)
    pfam08496
    Location:67115
    Peptidase_S49_N; Peptidase family S49 N-terminal
  2. NM_028903.2NP_083179.2  scavenger receptor class A member 5 isoform 1

    See identical proteins and their annotated locations for NP_083179.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK133176, BC016096
    Consensus CDS
    CCDS27214.1
    UniProtKB/Swiss-Prot
    Q8K299
    Related
    ENSMUSP00000022610.9, ENSMUST00000022610.15
    Conserved Domains (3) summary
    PRK09039
    Location:55249
    PRK09039; peptidoglycan -binding protein
    smart00202
    Location:389489
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:318373
    Collagen; Collagen triple helix repeat (20 copies)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    65903852..66002275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158851.1XP_036014744.1  scavenger receptor class A member 5 isoform X1

    Conserved Domains (3) summary
    PRK09039
    Location:55249
    PRK09039; peptidoglycan -binding protein
    smart00202
    Location:389489
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:318373
    Collagen; Collagen triple helix repeat (20 copies)
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