PTGES3 prostaglandin E synthase 3 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PTGES3provided by VGNC
Official Full Name: prostaglandin E synthase 3provided by VGNC
Primary source: VGNC:VGNC:97814
See related: Ensembl:ENSMMUG00000013766
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	11	NC_041764.1 (56240089..56266116, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	11	NC_027903.1 (55448045..55474328, complement)

Chromosome 11 - NC_041764.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:234880 (e-PCR)
- UniSTS:234880

RH92953 (e-PCR)
- UniSTS:87258

PTGES3 (e-PCR)
- UniSTS:504032

SHGC-75126 (e-PCR)
- UniSTS:29165

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Hsp90 protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables prostaglandin-E synthase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chaperone-mediated protein complex assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in prostaglandin biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein folding	IEA Inferred from Electronic Annotation more info	PubMed
involved_in telomerase holoenzyme complex assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in telomere maintenance via telomerase	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prostaglandin E synthase 3

Names: prostaglandin E synthase 3 (cytosolic)

NP_001248443.1

EC 5.3.99.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261514.1 → NP_001248443.1 prostaglandin E synthase 3

See identical proteins and their annotated locations for NP_001248443.1

Status: PROVISIONAL

Source sequence(s)

JV043433

UniProtKB/TrEMBL

F6Q847, H9EM56

Related

ENSMMUP00000047137.2, ENSMMUT00000074949.2

Conserved Domains (1) summary

cd00237
Location:3 → 109

p23; p23 binds heat shock protein (Hsp)90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis.