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LAMA2 laminin subunit alpha 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715394, updated on 5-Mar-2024

Summary

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Official Symbol
LAMA2provided by VGNC
Official Full Name
laminin subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:74225
See related
Ensembl:ENSMMUG00000022136
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
68
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (32303885..33078067)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (137979966..138591949, complement)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene elongation factor 1-delta-like Neighboring gene mesoderm-specific transcript homolog protein pseudogene Neighboring gene uncharacterized LOC114677486 Neighboring gene Rho GTPase activating protein 18 Neighboring gene UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2
Names
laminin, alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    32303885..33078067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028847101.1 → XP_028702934.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:1038 → 1082
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1302 → 1435
    LamB; Laminin B domain
    cd00055
    Location:900 → 945
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3012 → 3164
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1789 → 2148
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2108 → 2244
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1664 → 1923
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1131 → 1179
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2864 → 2992
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:14 → 250
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_015137478.2 → XP_014992964.2  laminin subunit alpha-2 isoform X7

    UniProtKB/TrEMBL
    F7H3A8, G7MQE4
    Related
    ENSMMUP00000029154.4, ENSMMUT00000031150.4
    Conserved Domains (10) summary
    smart00180
    Location:967 → 1011
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1231 → 1364
    LamB; Laminin B domain
    cd00055
    Location:917 → 965
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2941 → 3093
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1718 → 2077
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2037 → 2173
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1593 → 1852
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1060 → 1108
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2793 → 2921
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  3. XM_015137479.2 → XP_014992965.2  laminin subunit alpha-2 isoform X8

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:967 → 1011
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1231 → 1364
    LamB; Laminin B domain
    cd00055
    Location:917 → 965
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2937 → 3089
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1718 → 2077
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2037 → 2173
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1593 → 1852
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1060 → 1108
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2789 → 2917
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  4. XM_015137474.2 → XP_014992960.2  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:1073 → 1117
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1337 → 1470
    LamB; Laminin B domain
    cd00055
    Location:935 → 980
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3043 → 3195
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1824 → 2183
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2143 → 2279
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1699 → 1958
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1166 → 1214
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2895 → 3023
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  5. XM_015137473.2 → XP_014992959.2  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:1073 → 1117
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1337 → 1470
    LamB; Laminin B domain
    cd00055
    Location:935 → 980
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3045 → 3197
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1824 → 2183
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2143 → 2277
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1699 → 1958
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1166 → 1214
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2897 → 3025
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  6. XM_015137476.2 → XP_014992962.2  laminin subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:1073 → 1117
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1337 → 1470
    LamB; Laminin B domain
    cd00055
    Location:935 → 980
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3001 → 3153
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1778 → 2137
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2097 → 2233
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1653 → 1912
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1166 → 1214
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2853 → 2981
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  7. XM_015137477.2 → XP_014992963.2  laminin subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:985 → 1029
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1249 → 1382
    LamB; Laminin B domain
    cd00055
    Location:935 → 983
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2959 → 3111
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1736 → 2095
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2055 → 2191
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1611 → 1870
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1078 → 1126
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2811 → 2939
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)

  8. XM_015137475.2 → XP_014992961.2  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    G7MQE4
    Conserved Domains (10) summary
    smart00180
    Location:1055 → 1099
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1319 → 1452
    LamB; Laminin B domain
    cd00055
    Location:917 → 962
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3029 → 3181
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1806 → 2165
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2125 → 2261
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1681 → 1940
    Laminin_I; Laminin Domain I
    pfam00053
    Location:1148 → 1196
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2881 → 3009
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:49 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
Nucleotide Protein
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