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MTHFS methenyltetrahydrofolate synthetase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717493, updated on 5-Mar-2024

Summary

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Official Symbol
MTHFSprovided by VGNC
Official Full Name
methenyltetrahydrofolate synthetaseprovided by VGNC
Primary source
VGNC:VGNC:84401
Locus tag
EGK_17741
See related
Ensembl:ENSMMUG00000015224
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (57142008..57192712, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (57371984..57422646, complement)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114679468 Neighboring gene basic salivary proline-rich protein 2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5-formyltetrahydrofolate cyclo-ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in folic acid-containing compound biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-formyltetrahydrofolate cyclo-ligase
Names
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NP_001253007.1
XP_028706383.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266078.1 → NP_001253007.1  5-formyltetrahydrofolate cyclo-ligase

    See identical proteins and their annotated locations for NP_001253007.1

    Status: PROVISIONAL

    Source sequence(s)
    JV045948
    UniProtKB/TrEMBL
    A0A1D5QRQ4, A0A8J8XM46, F6VVW7, G7MYH0
    Related
    ENSMMUP00000050732.2, ENSMMUT00000075729.2
    Conserved Domains (1) summary
    pfam01812
    Location:10 → 198
    5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    57142008..57192712 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028850550.1 → XP_028706383.1  5-formyltetrahydrofolate cyclo-ligase isoform X1

    Conserved Domains (1) summary
    pfam01812
    Location:1 → 141
    5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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