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Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 71988, updated on 23-Jun-2021

Summary

Official Symbol
Esco2provided by MGI
Official Full Name
establishment of sister chromatid cohesion N-acetyltransferase 2provided by MGI
Primary source
MGI:MGI:1919238
See related
Ensembl:ENSMUSG00000022034
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410004I17Rik; D030072L07Rik
Expression
Biased expression in liver E14 (RPKM 10.1), liver E14.5 (RPKM 7.6) and 10 other tissues See more
Orthologs
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Genomic context

See Esco2 in Genome Data Viewer
Location:
14; 14 D1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66056476..66071418, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65819027..65833969, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66437864..66452806, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene scavenger receptor class A, member 5 Neighboring gene PDZ binding kinase Neighboring gene coiled-coil domain containing 25 Neighboring gene predicted gene, 41181

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in XY body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in chromocenter IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in site of double-strand break IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
N-acetyltransferase ESCO2
Names
ECO1 homolog 2
establishment of cohesion 1 homolog 2
NP_082315.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028039.2NP_082315.3  N-acetyltransferase ESCO2

    See identical proteins and their annotated locations for NP_082315.3

    Status: VALIDATED

    Source sequence(s)
    AA189671, AA881675, AK010391, AV216701, BY029949, CF168369, CF730483
    Consensus CDS
    CCDS27216.1
    UniProtKB/Swiss-Prot
    Q8CIB9
    Related
    ENSMUSP00000022613.10, ENSMUST00000022613.10
    Conserved Domains (2) summary
    pfam13878
    Location:371410
    zf-C2H2_3; zinc-finger of acetyl-transferase ESCO
    pfam13880
    Location:520582
    Acetyltransf_13; ESCO1/2 acetyl-transferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    66056476..66071418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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