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Ddx54 DEAD box helicase 54 [ Mus musculus (house mouse) ]

Gene ID: 71990, updated on 23-Jun-2021

Summary

Official Symbol
Ddx54provided by MGI
Official Full Name
DEAD box helicase 54provided by MGI
Primary source
MGI:MGI:1919240
See related
Ensembl:ENSMUSG00000029599
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AP; DP9; DP97; AI414901; 2410015A15Rik
Expression
Ubiquitous expression in thymus adult (RPKM 40.5), spleen adult (RPKM 29.4) and 28 other tissues See more
Orthologs
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Genomic context

See Ddx54 in Genome Data Viewer
Location:
5; 5 F
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (120751147..120766657)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (120613082..120628592)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (121063139..121078601)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene two pore channel 1 Neighboring gene IQ motif containing D Neighboring gene RBPJ interacting and tubulin associated 1 Neighboring gene cilia and flagella associated protein 73 Neighboring gene RAS protein activator like 1 (GAP1 like) Neighboring gene deltex 1, E3 ubiquitin ligase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity ISO
Inferred from Sequence Orthology
more info
 
enables estrogen receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in RNA processing ISO
Inferred from Sequence Orthology
more info
 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATP-dependent RNA helicase DDX54
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAD box protein 54
NP_082317.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028041.2NP_082317.1  ATP-dependent RNA helicase DDX54

    See identical proteins and their annotated locations for NP_082317.1

    Status: PROVISIONAL

    Source sequence(s)
    BC043699
    Consensus CDS
    CCDS39241.1
    UniProtKB/Swiss-Prot
    Q8K4L0
    Related
    ENSMUSP00000031598.10, ENSMUST00000031598.11
    Conserved Domains (4) summary
    COG0513
    Location:69537
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00079
    Location:314440
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:97299
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam08147
    Location:706766
    DBP10CT; DBP10CT (NUC160) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    120751147..120766657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_878688.3 RNA Sequence

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