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2510002D24Rik RIKEN cDNA 2510002D24 gene [ Mus musculus (house mouse) ]

Gene ID: 72307, updated on 11-Apr-2024

Summary

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Official Symbol
2510002D24Rikprovided by MGI
Official Full Name
RIKEN cDNA 2510002D24 geneprovided by MGI
Primary source
MGI:MGI:1919557
See related
Ensembl:ENSMUSG00000071632 AllianceGenome:MGI:1919557
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pants; DXMgi27; 2410043I01Rik
Summary
Is expressed in several structures, including brain; heart; liver; male reproductive gland or organ; and small intestine. Orthologous to human C22orf39 (chromosome 22 open reading frame 39). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 28.4), ovary adult (RPKM 25.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See 2510002D24Rik in Genome Data Viewer
Location:
16 A3; 16 11.67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (18655263..18658910)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (18836580..18840113)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 45 Neighboring gene predicted gene, 52240 Neighboring gene STARR-positive B cell enhancer ABC_E763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:18812268-18812501 Neighboring gene ubiquitin recognition factor in ER-associated degradation 1 Neighboring gene STARR-positive B cell enhancer ABC_E10892 Neighboring gene mitochondrial ribosomal protein L40 Neighboring gene histone cell cycle regulator Neighboring gene 60S ribosomal protein L27a-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age. Kragness S, et al. PLoS One, 2022. PMID 35771867, Free PMC Article
  2. Age-dependent expression pattern in the mammalian brain of a novel, small peptide encoded in the 22q11.2 deletion syndrome region. Kragness S, et al. Gene Expr Patterns, 2018 Jun. PMID 29571919
  3. Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium. Devaraju P, et al. Mol Psychiatry, 2017 Sep. PMID 27184122, Free PMC Article
  4. Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2. Lund J, et al. Genomics, 2000 Feb 1. PMID 10704284
  5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1)  1 citation

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in negative regulation of long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of synaptic plasticity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synaptic cleft IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
synaptic plasticity regulator PANTS
Names
UPF0545 protein C22orf39 homolog
plasticity-associated neural transcript

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033164.2 → NP_001028336.1  synaptic plasticity regulator PANTS

    See identical proteins and their annotated locations for NP_001028336.1

    Status: VALIDATED

    Source sequence(s)
    AK153794, AK160192
    Consensus CDS
    CCDS28029.1
    UniProtKB/Swiss-Prot
    Q3U595
    Related
    ENSMUSP00000060363.7, ENSMUST00000055413.13
    Conserved Domains (1) summary
    pfam11326
    Location:13 → 88
    DUF3128; Protein of unknown function (DUF3128)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    18655263..18658910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160137.1 → XP_036016030.1  synaptic plasticity regulator PANTS isoform X1

    UniProtKB/TrEMBL
    A0A087WS89
    Related
    ENSMUSP00000140943.2, ENSMUST00000123146.8
    Conserved Domains (1) summary
    pfam11326
    Location:23 → 74
    DUF3128; Protein of unknown function (DUF3128)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3U595.1 GenPept UniProtKB/Swiss-Prot:Q3U595

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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