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Faim2 Fas apoptotic inhibitory molecule 2 [ Mus musculus (house mouse) ]

Gene ID: 72393, updated on 23-Jun-2021

Summary

Official Symbol
Faim2provided by MGI
Official Full Name
Fas apoptotic inhibitory molecule 2provided by MGI
Primary source
MGI:MGI:1919643
See related
Ensembl:ENSMUSG00000023011
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lf; Lfg; NMP; Lfg2; NMP25; Nmp35; Tmbim; lifeg; Tmbim2; 2900002L20Rik
Expression
Biased expression in cerebellum adult (RPKM 23.5), frontal lobe adult (RPKM 16.4) and 5 other tissues See more
Orthologs
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Genomic context

See Faim2 in Genome Data Viewer
Location:
15; 15 F1
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (99394886..99432757, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99497005..99534880, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (99327436..99358448, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene NCK-associated protein 5-like Neighboring gene NCK-associated protein 5-like, opposite strand Neighboring gene BCDIN3 domain containing Neighboring gene predicted gene 5808 Neighboring gene predicted gene, 34765 Neighboring gene aquaporin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein lifeguard 2
Names
neural membrane protein 35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001038658.2NP_001033747.1  protein lifeguard 2 isoform 2

    See identical proteins and their annotated locations for NP_001033747.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK030513, AK158960, BC072560, CJ283203
    Consensus CDS
    CCDS88840.1
    UniProtKB/Swiss-Prot
    Q8K097
    Related
    ENSMUSP00000155195.2, ENSMUST00000231171.2
    Conserved Domains (1) summary
    cd10428
    Location:81301
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis
  2. NM_028224.4NP_082500.2  protein lifeguard 2 isoform 1

    See identical proteins and their annotated locations for NP_082500.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK030513, AK158960, BC072560, CJ283203
    Consensus CDS
    CCDS37203.1
    UniProtKB/Swiss-Prot
    Q8K097
    Related
    ENSMUSP00000023750.8, ENSMUST00000023750.9
    Conserved Domains (1) summary
    cd10428
    Location:93313
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    99394886..99432757 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521449.5XP_006521512.1  protein lifeguard 2 isoform X1

    See identical proteins and their annotated locations for XP_006521512.1

    UniProtKB/Swiss-Prot
    Q8K097
    Conserved Domains (1) summary
    cd10428
    Location:93313
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis
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