Ift70b intraflagellar transport 70B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ift70bprovided by MGI
Official Full Name: intraflagellar transport 70Bprovided by MGI
Primary source: MGI:MGI:1919671
See related: Ensembl:ENSMUSG00000075273 AllianceGenome:MGI:1919671
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Tcc30b; Ttc30b; 2510042P03Rik
Summary: Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to act upstream of or within cell projection organization. Part of intraciliary transport particle B. Orthologous to several human genes including TTC30B (tetratricopeptide repeat domain 30B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 2 C3; 2 44.79 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (75766193..75768806, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (75935849..75938462, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables intraciliary transport particle B binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell projection organization	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	NAS Non-traceable Author Statement more info	PubMed
involved_in intraciliary anterograde transport	NAS Non-traceable Author Statement more info	PubMed
involved_in intraciliary transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intraciliary transport	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
is_active_in axonemal microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info	PubMed
located_in cilium	IC Inferred by Curator more info	PubMed
located_in cilium	NAS Non-traceable Author Statement more info	PubMed
part_of intraciliary transport particle B	IBA Inferred from Biological aspect of Ancestor more info
part_of intraciliary transport particle B	IDA Inferred from Direct Assay more info	PubMed
part_of intraciliary transport particle B	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: intraflagellar transport protein 70B

Names: TPR repeat protein 30B; novel tetratrico peptide repeat (TPR) containing protein; tetratricopeptide repeat domain 30B; tetratricopeptide repeat protein 30B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_028235.1 → NP_082511.1 intraflagellar transport protein 70B

See identical proteins and their annotated locations for NP_082511.1

Status: VALIDATED

Source sequence(s)

AL773533, BC026507

Consensus CDS

CCDS38150.1

UniProtKB/Swiss-Prot

Q3UI02, Q9CY00

UniProtKB/TrEMBL

B2RXA2

Related

ENSMUSP00000097576.4, ENSMUST00000099996.5

Conserved Domains (2) summary

TIGR02917
Location:15 → 216

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:157 → 181

TPR; TPR repeat [structural motif]