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NPIPB11 nuclear pore complex interacting protein family member B11 [ Homo sapiens (human) ]

Gene ID: 728888, updated on 13-Aug-2021

Summary

Official Symbol
NPIPB11provided by HGNC
Official Full Name
nuclear pore complex interacting protein family member B11provided by HGNC
Primary source
HGNC:HGNC:37453
See related
Ensembl:ENSG00000254206
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NPIP
Expression
Ubiquitous expression in skin (RPKM 25.8), bone marrow (RPKM 16.9) and 24 other tissues See more
Orthologs
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Genomic context

See NPIPB11 in Genome Data Viewer
Location:
16p11.2
Exon count:
11
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (29381318..29404545, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (29392639..29415866, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371159 Neighboring gene translation initiation factor IF-2-like Neighboring gene sorting nexin 29 pseudogene 2 Neighboring gene SMG1 pseudogene 6 Neighboring gene BOLA2-SMG1P6 readthrough Neighboring gene coronin 1A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
nuclear pore complex-interacting protein family member B11
Names
NPIP-like locus
hepatitis B virus pre-pre-S promoter DNA-binding protein
pps22-1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310137.4NP_001297066.2  nuclear pore complex-interacting protein family member B11

    Status: VALIDATED

    Source sequence(s)
    AC025279
    Related
    ENSP00000430853.1, ENST00000524087.5
    Conserved Domains (3) summary
    PTZ00449
    Location:10041161
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam06409
    Location:46303
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl17068
    Location:241
    AFD_class_I; Adenylate forming domain, Class I superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    29381318..29404545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450420.1XP_024306188.1  nuclear pore complex-interacting protein family member B11 isoform X1

    Conserved Domains (3) summary
    pfam06409
    Location:70250
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl17068
    Location:141
    AFD_class_I; Adenylate forming domain, Class I superfamily
    cl28033
    Location:9121151
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
  2. XM_024450421.1XP_024306189.1  nuclear pore complex-interacting protein family member B11 isoform X2

    Conserved Domains (2) summary
    pfam06409
    Location:70250
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl17068
    Location:141
    AFD_class_I; Adenylate forming domain, Class I superfamily
  3. XM_024450422.1XP_024306190.1  nuclear pore complex-interacting protein family member B11 isoform X3

    Related
    ENSP00000479201.1, ENST00000614927.1
    Conserved Domains (1) summary
    pfam06409
    Location:26200
    NPIP; Nuclear pore complex interacting protein (NPIP)
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