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hnf1b HNF1 homeobox B [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 733490, updated on 5-Mar-2024

Summary

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Official Symbol
hnf1bprovided by Xenbase
Official Full Name
HNF1 homeobox Bprovided by Xenbase
Primary source
Xenbase:XB-GENE-485652
See related
Ensembl:ENSXETG00000008000
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
fjhn; hnf2; lfb3; tcf2; mody5; vhnf1; hnf1beta; hnf-1beta; hnf1-beta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
10
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (74694403..74720550, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (48874183..48899621, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene presenilin associated, rhomboid-like Neighboring gene transmembrane protein 167B Neighboring gene HEAT repeat containing 6 protein Neighboring gene dynein light chain LC8-type 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hnf1b renal expression directed by a distal enhancer responsive to Pax8. Goea L, et al. Sci Rep, 2022 Nov 19. PMID 36402859, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Hnf1b renal expression directed by a distal enhancer responsive to Pax8.
    Title: Hnf1b renal expression directed by a distal enhancer responsive to Pax8.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Clone Names

  • MGC68954

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within animal organ development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within insulin secretion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within liver development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pancreas development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within system development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hepatocyte nuclear factor 1-beta
Names
transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    74694403..74720550 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002939633.5 → XP_002939679.1  hepatocyte nuclear factor 1-beta isoform X1

    UniProtKB/TrEMBL
    F6XA53
    Related
    ENSXETP00000017532.3, ENSXETT00000017532.5
    Conserved Domains (3) summary
    smart00389
    Location:230 → 304
    HOX; Homeodomain
    pfam04812
    Location:313 → 554
    HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C-terminus
    pfam04814
    Location:8 → 173
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N-terminus

  2. XM_018091502.2 → XP_017946991.1  hepatocyte nuclear factor 1-beta isoform X2

    UniProtKB/TrEMBL
    A0A8J0SYI4
    Conserved Domains (3) summary
    smart00389
    Location:137 → 211
    HOX; Homeodomain
    pfam04812
    Location:220 → 461
    HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C-terminus
    pfam04814
    Location:17 → 80
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N-terminus
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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