Nudt16l2 nudix hydrolase 16 like 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nudt16l2provided by MGI
Official Full Name: nudix hydrolase 16 like 2provided by MGI
Primary source: MGI:MGI:1920782
See related: Ensembl:ENSMUSG00000032566 AllianceGenome:MGI:1920782
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Tseg8; 1700080E11Rik
Summary: Predicted to enable several functions, including RNA binding activity; metal ion binding activity; and purine ribonucleoside triphosphate binding activity. Predicted to be involved in mRNA catabolic process and sno(s)RNA catabolic process. Predicted to be located in cytoplasm; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in testis. Orthologous to several human genes including NUDT16 (nudix hydrolase 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward testis adult (RPKM 106.7) See more
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Genomic context

Location:: 9 F1; 9 56.61 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (105020543..105022281, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (105143344..105145082, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity	IEA Inferred from Electronic Annotation more info
enables IDP phosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphodiesterase decapping endonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables snoRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mRNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sno(s)RNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: U8 snoRNA-decapping enzyme-like

Names: nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 2; nudix motif 16-like; testis specific expressed protein 8

NP_082838.2

EC 3.6.1.62

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_028562.3 → NP_082838.2 U8 snoRNA-decapping enzyme-like

Status: VALIDATED

Source sequence(s)

AC161250

Consensus CDS

CCDS23463.1

UniProtKB/TrEMBL

C9W8M5, E9Q9G1

Related

ENSMUSP00000035180.4, ENSMUST00000035180.5

Conserved Domains (1) summary

cl00447
Location:54 → 94

Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...