Format

Send to:

Choose Destination

Cmtr1 cap methyltransferase 1 [ Mus musculus (house mouse) ]

Gene ID: 74157, updated on 23-Jun-2021

Summary

Official Symbol
Cmtr1provided by MGI
Official Full Name
cap methyltransferase 1provided by MGI
Primary source
MGI:MGI:1921407
See related
Ensembl:ENSMUSG00000024019
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MTr1; Ftsjd; Ftsjd2; AI451264; 1300018I05Rik
Expression
Ubiquitous expression in cerebellum adult (RPKM 14.8), CNS E14 (RPKM 12.4) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Cmtr1 in Genome Data Viewer
Location:
17; 17 A3.3
Exon count:
24
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (29879569..29924953)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (29660595..29705979)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (29797546..29840304)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 28043 Neighboring gene ring finger protein 8 Neighboring gene predicted gene, 20161 Neighboring gene coiled-coil domain containing 167 Neighboring gene MAM domain containing glycosylphosphatidylinositol anchor 1 Neighboring gene predicted gene, 41559 Neighboring gene predicted gene, 22327

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough Gm28043

Readthrough gene: Gm28043, Included gene: Rnf8

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA (nucleoside-2'-O-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA (nucleoside-2'-O-)-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in 7-methylguanosine mRNA capping IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in 7-methylguanosine mRNA capping ISO
Inferred from Sequence Orthology
more info
 
involved_in cap1 mRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cap1 mRNA methylation ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA methylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in methylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Names
FtsJ methyltransferase domain-containing protein 2
S-adenosyl-L-methionine-dependent methyltransferase FTSJD2
cap1 2'O-ribose methyltransferase 1
NP_083067.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028791.6NP_083067.1  cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

    See identical proteins and their annotated locations for NP_083067.1

    Status: VALIDATED

    Source sequence(s)
    AK005044, AK080379, AW050293, BC056481, BC080305, BY290726, CF746189
    Consensus CDS
    CCDS37539.1
    UniProtKB/Swiss-Prot
    Q9DBC3
    Related
    ENSMUSP00000024816.7, ENSMUST00000024816.13
    Conserved Domains (3) summary
    pfam01585
    Location:86128
    G-patch; G-patch domain
    pfam01728
    Location:231447
    FtsJ; FtsJ-like methyltransferase
    cl12015
    Location:622739
    Adenylation_DNA_ligase_like; Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    29879569..29924953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center