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Cldnd2 claudin domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 74276, updated on 5-Mar-2024

Summary

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Official Symbol
Cldnd2provided by MGI
Official Full Name
claudin domain containing 2provided by MGI
Primary source
MGI:MGI:1921526
See related
Ensembl:ENSMUSG00000038973 AllianceGenome:MGI:1921526
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700071E18Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human CLDND2 (claudin domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 34.5) See more
Orthologs
human all
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Genomic context

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Location:
7 B3; 7 28.25 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43090164..43093554)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43440740..43444130)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene lens intrinsic membrane protein 2 Neighboring gene natural killer cell group 7 sequence Neighboring gene STARR-positive B cell enhancer ABC_E9689 Neighboring gene electron transferring flavoprotein, beta polypeptide Neighboring gene microRNA 7051 Neighboring gene predicted gene, 39000 Neighboring gene STARR-positive B cell enhancer ABC_E4923 Neighboring gene V-set and immunoglobulin domain containing 10 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
claudin domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418965.1 → NP_001405894.1  claudin domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC149091, AC154108

  2. NM_028849.2 → NP_083125.1  claudin domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_083125.1

    Status: VALIDATED

    Source sequence(s)
    AC149091, AC154108
    Consensus CDS
    CCDS39929.1
    UniProtKB/Swiss-Prot
    Q9D9H2
    UniProtKB/TrEMBL
    A1A539
    Related
    ENSMUSP00000037980.2, ENSMUST00000040227.3
    Conserved Domains (1) summary
    cl21598
    Location:23 → 144
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    43090164..43093554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030243028.2 → XP_030098888.1  claudin domain-containing protein 2 isoform X2

    Conserved Domains (1) summary
    cl21598
    Location:23 → 144
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  2. XM_017312349.2 → XP_017167838.1  claudin domain-containing protein 2 isoform X1

    Conserved Domains (1) summary
    cl21598
    Location:23 → 140
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  3. XM_030243029.1 → XP_030098889.1  claudin domain-containing protein 2 isoform X3

    Conserved Domains (1) summary
    cl21598
    Location:23 → 140
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  4. XM_030243031.1 → XP_030098891.1  claudin domain-containing protein 2 isoform X5

    UniProtKB/Swiss-Prot
    Q9D9H2
    UniProtKB/TrEMBL
    A1A539
    Conserved Domains (1) summary
    cl21598
    Location:23 → 144
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  5. XM_030243030.1 → XP_030098890.1  claudin domain-containing protein 2 isoform X4

    Conserved Domains (1) summary
    cl21598
    Location:23 → 144
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D9H2.1 GenPept UniProtKB/Swiss-Prot:Q9D9H2

Gene LinkOut

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