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IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 [ Pan troglodytes (chimpanzee) ]

Gene ID: 744246, updated on 29-Mar-2024

Summary

Official Symbol
IGF2BP3provided by VGNC
Official Full Name
insulin like growth factor 2 mRNA binding protein 3provided by VGNC
Primary source
VGNC:VGNC:4396
Locus tag
CK820_G0034696
See related
Ensembl:ENSPTRG00000018986
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 7
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (29136875..29290598, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (26911088..27064501, complement)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene glycoprotein nmb Neighboring gene mitochondrial assembly of ribosomal large subunit 1 Neighboring gene small nucleolar RNA SNORD65 Neighboring gene U7 small nuclear RNA Neighboring gene neuronal regeneration-related protein-like Neighboring gene small ribosomal subunit protein uS5-like

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
insulin-like growth factor 2 mRNA-binding protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    29136875..29290598 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001157593.7XP_001157593.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_001157593.1

    UniProtKB/TrEMBL
    A0A2J8KZF4, A0A6D2X2Z9, H2QU96
    Related
    ENSPTRP00000032446.3
    Conserved Domains (5) summary
    cd00105
    Location:279344
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:407470
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    cd12627
    Location:177
    RRM1_IGF2BP3; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cd12630
    Location:81156
    RRM2_IGF2BP3; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    pfam00013
    Location:492555
    KH_1; KH domain
  2. XM_016957164.4XP_016812653.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X4

    Conserved Domains (5) summary
    COG0724
    Location:291
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00105
    Location:224289
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:352415
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    cd12627
    Location:177
    RRM1_IGF2BP3; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cl17169
    Location:78101
    RRM_SF; RNA recognition motif (RRM) superfamily
  3. XM_063814126.1XP_063670196.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X3

  4. XM_063814125.1XP_063670195.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X2

  5. XM_063814127.1XP_063670197.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X6

  6. XM_054687433.2XP_054543408.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X5