Format

Send to:

Choose Destination

Morc2a microrchidia 2A [ Mus musculus (house mouse) ]

Gene ID: 74522, updated on 8-Jul-2021

Summary

Official Symbol
Morc2aprovided by MGI
Official Full Name
microrchidia 2Aprovided by MGI
Primary source
MGI:MGI:1921772
See related
Ensembl:ENSMUSG00000034543
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zcwcc1; 8430403M08Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 13.7), CNS E14 (RPKM 13.3) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Morc2a in Genome Data Viewer
Location:
11; 11 A1
Exon count:
27
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (3599132..3640477)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (3649189..3690477)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (3549497..3590375)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11951 Neighboring gene taurine upregulated gene 1 Neighboring gene nucleolar and spindle associated protein 1 pseudogene Neighboring gene oxysterol binding protein 2 Neighboring gene predicted gene, 51881

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
 
enables histone binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in heterochromatin ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATPase MORC2A
Names
MORC family CW-type zinc finger protein 2A
zinc finger CW-type coiled-coil domain protein 1
zinc finger, CW-type with coiled-coil domain 1
NP_001152760.1
NP_001350131.1
NP_937805.1
XP_006514934.1
XP_011242077.1
XP_036012945.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159288.2NP_001152760.1  ATPase MORC2A isoform 1

    See identical proteins and their annotated locations for NP_001152760.1

    Status: VALIDATED

    Source sequence(s)
    AK173042, AL691413
    Consensus CDS
    CCDS48741.1
    UniProtKB/Swiss-Prot
    Q69ZX6
    Related
    ENSMUSP00000091087.3, ENSMUST00000093389.9
    Conserved Domains (3) summary
    pfam07496
    Location:495542
    zf-CW; CW-type Zinc Finger
    pfam13589
    Location:29169
    HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
    cl26464
    Location:624741
    Atrophin-1; Atrophin-1 family
  2. NM_001363202.1NP_001350131.1  ATPase MORC2A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL691413
    Consensus CDS
    CCDS48741.1
    Related
    ENSMUSP00000094176.4, ENSMUST00000096441.5
    Conserved Domains (3) summary
    pfam07496
    Location:495542
    zf-CW; CW-type Zinc Finger
    pfam13589
    Location:29169
    HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
    cl26464
    Location:624741
    Atrophin-1; Atrophin-1 family
  3. NM_198162.2NP_937805.1  ATPase MORC2A isoform 2

    See identical proteins and their annotated locations for NP_937805.1

    Status: VALIDATED

    Source sequence(s)
    AL691413, BC059243
    UniProtKB/TrEMBL
    Q6PCN6
    Conserved Domains (4) summary
    PHA03247
    Location:562679
    PHA03247; large tegument protein UL36; Provisional
    pfam07496
    Location:433480
    zf-CW; CW-type Zinc Finger
    pfam17942
    Location:177389
    Morc6_S5; Morc6 ribosomal protein S5 domain 2-like
    cl00075
    Location:173
    HATPase; Histidine kinase-like ATPase domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    3599132..3640477
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243775.4XP_011242077.1  ATPase MORC2A isoform X1

    See identical proteins and their annotated locations for XP_011242077.1

    Conserved Domains (4) summary
    PHA03247
    Location:624741
    PHA03247; large tegument protein UL36; Provisional
    cd16931
    Location:18135
    HATPase_MORC-like; Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains
    pfam07496
    Location:495542
    zf-CW; CW-type Zinc Finger
    pfam17942
    Location:239451
    Morc6_S5; Morc6 ribosomal protein S5 domain 2-like
  2. XM_006514871.4XP_006514934.1  ATPase MORC2A isoform X1

    See identical proteins and their annotated locations for XP_006514934.1

    Conserved Domains (4) summary
    PHA03247
    Location:624741
    PHA03247; large tegument protein UL36; Provisional
    cd16931
    Location:18135
    HATPase_MORC-like; Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains
    pfam07496
    Location:495542
    zf-CW; CW-type Zinc Finger
    pfam17942
    Location:239451
    Morc6_S5; Morc6 ribosomal protein S5 domain 2-like
  3. XM_036157052.1XP_036012945.1  ATPase MORC2A isoform X2

    Conserved Domains (4) summary
    PHA03247
    Location:562679
    PHA03247; large tegument protein UL36; Provisional
    pfam07496
    Location:433480
    zf-CW; CW-type Zinc Finger
    pfam17942
    Location:177389
    Morc6_S5; Morc6 ribosomal protein S5 domain 2-like
    cl00075
    Location:173
    HATPase; Histidine kinase-like ATPase domain
Support Center