SYDE1 synapse defective Rho GTPase homolog 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: SYDE1provided by VGNC
Official Full Name: synapse defective Rho GTPase homolog 1provided by VGNC
Primary source: VGNC:VGNC:10271
Locus tag: CK820_G0026262
See related: Ensembl:ENSPTRG00000010613
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	20	NC_072418.2 (17799693..17807291)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	19	NC_072417.1 (17799735..17807345)

Chromosome 20 - NC_072418.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

ILVBL_9207 (e-PCR)
- UniSTS:468481

RH12226 (e-PCR)
- UniSTS:77354

D19S849 (e-PCR)
- UniSTS:6959

RH16634 (e-PCR)
- UniSTS:27742

SGC33062 (e-PCR)
- UniSTS:63080

WI-11575 (e-PCR)
- UniSTS:63081

D19S825 (e-PCR)
- UniSTS:52927

D19S647E (e-PCR)
- UniSTS:8164

RH12349 (e-PCR)
- UniSTS:45028

D2S1729E (e-PCR)
- UniSTS:150758

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of Ras protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in synaptic membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho GTPase-activating protein SYDE1

Names: synapse defective 1, Rho GTPase, homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

17799693..17807291

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003316162.6 → XP_003316210.1 rho GTPase-activating protein SYDE1

See identical proteins and their annotated locations for XP_003316210.1

UniProtKB/TrEMBL

A0A2J8LUD0, A0A2J8LUD4, A0A6D2X4C5, H2QFL6

Related

ENSPTRP00000018111.4

Conserved Domains (1) summary

cl02570
Location:396 → 601

RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...