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Tmem65 transmembrane protein 65 [ Mus musculus (house mouse) ]

Gene ID: 74868, updated on 23-Jun-2021

Summary

Official Symbol
Tmem65provided by MGI
Official Full Name
transmembrane protein 65provided by MGI
Primary source
MGI:MGI:1922118
See related
Ensembl:ENSMUSG00000062373
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610029O13Rik; 4930438D12Rik
Expression
Ubiquitous expression in heart adult (RPKM 30.6), cerebellum adult (RPKM 15.8) and 26 other tissues See more
Orthologs
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Genomic context

See Tmem65 in Genome Data Viewer
Location:
15; 15 D1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (58654118..58695510, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (58782269..58823663, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (58613824..58654982, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene fer-1-like 6 (C. elegans) Neighboring gene predicted gene, 36451 Neighboring gene predicted gene, 41329 Neighboring gene predicted gene, 24041 Neighboring gene tRNA methyltransferase 12 Neighboring gene predicted gene, 36509

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cardiac ventricle development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cardiac ventricle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cardiac conduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cardiac conduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intercalated disc IDA
Inferred from Direct Assay
more info
PubMed 
located_in intercalated disc ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175212.4NP_780421.2  transmembrane protein 65

    See identical proteins and their annotated locations for NP_780421.2

    Status: PROVISIONAL

    Source sequence(s)
    AC107772
    Consensus CDS
    CCDS27493.1
    UniProtKB/Swiss-Prot
    Q4VAE3
    Related
    ENSMUSP00000071984.6, ENSMUST00000072113.6
    Conserved Domains (1) summary
    pfam10507
    Location:114221
    DUF2453; Protein of unknown function (DUF2453)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    58654118..58695510 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521504.5XP_006521567.1  transmembrane protein 65 isoform X1

    Conserved Domains (1) summary
    pfam10507
    Location:141248
    TMEM65; Transmembrane protein 65
  2. XM_036159621.1XP_036015514.1  transmembrane protein 65 isoform X2

    Conserved Domains (1) summary
    pfam10507
    Location:36143
    TMEM65; Transmembrane protein 65
  3. XM_011245759.4XP_011244061.1  transmembrane protein 65 isoform X3

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