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Rprd2 regulation of nuclear pre-mRNA domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 75137, updated on 23-Jun-2021

Summary

Official Symbol
Rprd2provided by MGI
Official Full Name
regulation of nuclear pre-mRNA domain containing 2provided by MGI
Primary source
MGI:MGI:1922387
See related
Ensembl:ENSMUSG00000028106
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AL022841; AL022940; AU021304; BB077382; mKIAA0460; 2810036A19Rik; 4930535B03Rik; 6720469I21Rik
Expression
Ubiquitous expression in thymus adult (RPKM 5.3), limb E14.5 (RPKM 5.0) and 28 other tissues See more
Orthologs
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Genomic context

See Rprd2 in Genome Data Viewer
Location:
3; 3 F2.1
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95667183..95727034, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95759871..95819744, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (95563796..95622876, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene microRNA 7014 Neighboring gene extracellular matrix protein 1 Neighboring gene threonyl-tRNA synthetase 2, mitochondrial (putative) Neighboring gene predicted gene, 26361 Neighboring gene lactate dehydrogenase A pseudogene Neighboring gene predicted gene, 29948 Neighboring gene pre-mRNA processing factor 3 Neighboring gene mitochondrial ribosomal protein S21

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA polymerase II complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in mRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II, holoenzyme IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of RNA polymerase II, holoenzyme ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
regulation of nuclear pre-mRNA domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081293.2NP_001074762.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001074762.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC093317, BC067054
    Consensus CDS
    CCDS38549.1
    UniProtKB/Swiss-Prot
    Q6NXI6
    Related
    ENSMUSP00000088297.4, ENSMUST00000090791.8
    Conserved Domains (1) summary
    smart00582
    Location:27145
    RPR; domain present in proteins, which are involved in regulation of nuclear pre-mRNA
  2. NM_001368178.1NP_001355107.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC093317, FQ790371
  3. NM_001368179.1NP_001355108.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC093317, FQ790371
    Related
    ENSMUSP00000143333.2, ENSMUST00000200164.5
  4. NM_001368180.1NP_001355109.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC093317
  5. NM_001368181.1NP_001355110.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC093317
  6. NM_028328.2NP_082604.2  regulation of nuclear pre-mRNA domain-containing protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC093317
    Consensus CDS
    CCDS89669.1
    Related
    ENSMUSP00000143240.2, ENSMUST00000197449.2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    95667183..95727034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252863.2XP_030108723.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform X1

    Conserved Domains (3) summary
    PRK03918
    Location:142318
    PRK03918; DNA double-strand break repair ATPase Rad50
    pfam05109
    Location:319645
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cd17001
    Location:27146
    CID_RPRD2; CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 2
  2. XM_011240267.4XP_011238569.1  regulation of nuclear pre-mRNA domain-containing protein 2 isoform X2

    Conserved Domains (2) summary
    pfam05109
    Location:293619
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cd17001
    Location:27145
    CID_RPRD2; CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_029180.1: Suppressed sequence

    Description
    NM_029180.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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