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mtrA two-component system response regulator MtrA [ Streptomyces albus ]

Gene ID: 75183339, updated on 14-Sep-2023

Summary

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Gene symbol
mtrA
Gene description
two-component system response regulator MtrA
Locus tag
NR995_RS19885
Gene type
protein coding
Organism
Streptomyces albus (strain: DSM 40763, culture-collection: DSM:40763)
Lineage
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Old locus tag
NR995_19885
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Genomic context

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NZ_CP103060.1Genomic Context describing neighboring genes Neighboring gene DUF4350 domain-containing protein Neighboring gene DUF4129 domain-containing protein Neighboring gene hypothetical protein Neighboring gene S-methyl-5-thioribose-1-phosphate isomerase Neighboring gene MtrAB system histidine kinase MtrB Neighboring gene LpqB family beta-propeller domain-containing protein Neighboring gene ComF family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP103060.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The developmental regulator MtrA binds GlnR boxes and represses nitrogen metabolism genes in Streptomyces coelicolor. Zhu Y, et al. Mol Microbiol, 2019 Jul. PMID 30927282
  2. Global mapping of MtrA-binding sites links MtrA to regulation of its targets in Mycobacterium tuberculosis. Chatterjee A, et al. Microbiology (Reading), 2018 Jan. PMID 29182512
  3. Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation. Friedland N, et al. Biochemistry, 2007 Jun 12. PMID 17511470, Free PMC Article
  4. Modulation of Mycobacterium tuberculosis proliferation by MtrA, an essential two-component response regulator. Fol M, et al. Mol Microbiol, 2006 May. PMID 16629667
  5. MtrA, an essential response regulator of the MtrAB two-component system, regulates the transcription of resuscitation-promoting factor B of Mycobacterium tuberculosis. Sharma AK, et al. Microbiology (Reading), 2015 Jun. PMID 25833257

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
two-component system response regulator MtrA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP103060.1 Reference assembly

    Range
    4667036..4667713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_016469303.1 MULTISPECIES: two-component system response regulator MtrA [Streptomyces]

    See identical proteins and their annotated locations for WP_016469303.1

    UniProtKB/TrEMBL
    A0A6C1C2F8, S3C289
    Conserved Domains (1) summary
    COG0745
    Location:4 → 221
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
Nucleotide Protein
Heading Accession and Version