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Tmco5b transmembrane and coiled-coil domains 5B [ Mus musculus (house mouse) ]

Gene ID: 75275, updated on 8-Feb-2024

Summary

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Official Symbol
Tmco5bprovided by MGI
Official Full Name
transmembrane and coiled-coil domains 5Bprovided by MGI
Primary source
MGI:MGI:1922525
See related
Ensembl:ENSMUSG00000041255 AllianceGenome:MGI:1922525
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930563P21Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMCO5B (transmembrane and coiled-coil domains 5B (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 7.5) See more
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Genomic context

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Location:
2 E4; 2 57.3 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (113115440..113127535)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (113285095..113297190)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 22676 Neighboring gene cholinergic receptor, muscarinic 5 Neighboring gene STARR-positive B cell enhancer mm9_chr2:112443695-112443995 Neighboring gene apoptosis, caspase activation inhibitor Neighboring gene STARR-seq mESC enhancer starr_05389 Neighboring gene STARR-seq mESC enhancer starr_05390 Neighboring gene ryanodine receptor 3 Neighboring gene STARR-seq mESC enhancer starr_05392 Neighboring gene STARR-seq mESC enhancer starr_05393 Neighboring gene STARR-seq mESC enhancer starr_05394 Neighboring gene STARR-seq mESC enhancer starr_05395 Neighboring gene predicted gene, 26505 Neighboring gene STARR-seq mESC enhancer starr_05396 Neighboring gene STARR-seq mESC enhancer starr_05397 Neighboring gene STARR-seq mESC enhancer starr_05399 Neighboring gene formin 1 Neighboring gene STARR-seq mESC enhancer starr_05401 Neighboring gene RIKEN cDNA 4930533B01 gene Neighboring gene predicted gene, 54142

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region. Pavel E, et al. Int J Dev Biol, 2007. PMID 17554679
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane and coiled-coil domain-containing protein 5B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029232.2 → NP_083508.1  transmembrane and coiled-coil domain-containing protein 5B

    See identical proteins and their annotated locations for NP_083508.1

    Status: VALIDATED

    Source sequence(s)
    BC050803
    Consensus CDS
    CCDS16558.1
    UniProtKB/Swiss-Prot
    Q80X59, Q9D4S7
    Related
    ENSMUSP00000042247.3, ENSMUST00000040856.3
    Conserved Domains (1) summary
    pfam14992
    Location:30 → 306
    TMCO5; TMCO5 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    113115440..113127535
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500326.1 → XP_006500389.1  transmembrane and coiled-coil domain-containing protein 5B isoform X1

    Conserved Domains (1) summary
    pfam14992
    Location:35 → 311
    TMCO5; TMCO5 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80X59.1 GenPept UniProtKB/Swiss-Prot:Q80X59

Gene LinkOut

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