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Lamp5 lysosomal-associated membrane protein family, member 5 [ Mus musculus (house mouse) ]

Gene ID: 76161, updated on 6-May-2021

Summary

Official Symbol
Lamp5provided by MGI
Official Full Name
lysosomal-associated membrane protein family, member 5provided by MGI
Primary source
MGI:MGI:1923411
See related
Ensembl:ENSMUSG00000027270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BAD-; LAMP-5; BAD-LAMP; 3110035N03Rik; 6330527O06Rik
Expression
Biased expression in cortex adult (RPKM 56.6), frontal lobe adult (RPKM 36.0) and 3 other tissues See more
Orthologs
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Genomic context

See Lamp5 in Genome Data Viewer
Location:
2; 2 F3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (135893945..135911837)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (136052025..136069917)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (135883663..135895653)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phospholipase C, beta 4 Neighboring gene uncharacterized LOC118568538 Neighboring gene predicted gene, 26227 Neighboring gene p21 (RAC1) activated kinase 5 Neighboring gene predicted gene 14218 Neighboring gene predicted gene, 39942

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in establishment of protein localization to organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendrite membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in early endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum-Golgi intermediate compartment membrane ISO
Inferred from Sequence Orthology
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endosome membrane ISO
Inferred from Sequence Orthology
more info
 
located_in growth cone membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in late endosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in lysosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in recycling endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lysosome-associated membrane glycoprotein 5
Names
LAMP family protein C20orf103 homolog
Protein C20orf103
brain and dendritic cell-associated LAMP
brain-associated LAMP-like protein
lysosome-associated membrane protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356548.1NP_001343477.1  lysosome-associated membrane glycoprotein 5 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AL845354, AL928798
    Consensus CDS
    CCDS16789.1
    Conserved Domains (1) summary
    pfam01299
    Location:43213
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)
  2. NM_029530.3NP_083806.2  lysosome-associated membrane glycoprotein 5 precursor

    See identical proteins and their annotated locations for NP_083806.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AL845354, AL928798
    Consensus CDS
    CCDS16789.1
    UniProtKB/Swiss-Prot
    Q9D387
    Related
    ENSMUSP00000061180.7, ENSMUST00000057503.7
    Conserved Domains (1) summary
    pfam01299
    Location:43213
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    135893945..135911837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319318.2XP_017174807.1  lysosome-associated membrane glycoprotein 5 isoform X2

    UniProtKB/Swiss-Prot
    Q9D387
    Conserved Domains (1) summary
    pfam01299
    Location:2495
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)
  2. XM_036162664.1XP_036018557.1  lysosome-associated membrane glycoprotein 5 isoform X1

    Conserved Domains (1) summary
    pfam01299
    Location:43213
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)

RNA

  1. XR_004940765.1 RNA Sequence

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