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Psapl1 prosaposin-like 1 [ Mus musculus (house mouse) ]

Gene ID: 76943, updated on 3-Apr-2024

Summary

Official Symbol
Psapl1provided by MGI
Official Full Name
prosaposin-like 1provided by MGI
Primary source
MGI:MGI:1924193
See related
Ensembl:ENSMUSG00000043430 AllianceGenome:MGI:1924193
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310020A21Rik
Summary
Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; prostate gland development; and regulation of lipid metabolic process. Predicted to be located in cytosol. Predicted to be active in extracellular space. Is expressed in lower urinary tract; naris; rectum; and vibrissa. Orthologous to human PSAPL1 (prosaposin like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
5 B3; 5 19.14 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (36361365..36363912)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (36204021..36206568)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene sortilin-related VPS10 domain containing receptor 2 Neighboring gene STARR-seq mESC enhancer starr_12872 Neighboring gene predicted gene, 32119 Neighboring gene predicted gene, 31945 Neighboring gene microRNA 7689 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36701008-36701161 Neighboring gene STARR-positive B cell enhancer mm9_chr5:36715900-36716201 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36720744-36720945 Neighboring gene RIKEN cDNA 2210406O10 gene

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in epithelial cell differentiation involved in prostate gland development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in prostate gland growth IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within sphingolipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in sphingolipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
proactivator polypeptide-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175249.4NP_780458.3  proactivator polypeptide-like 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC133937
    Consensus CDS
    CCDS39072.1
    UniProtKB/Swiss-Prot
    Q8BJV5, Q8C1C1, Q8C1N0
    Related
    ENSMUSP00000100594.2, ENSMUST00000052224.6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    36361365..36363912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)