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Zfp934 zinc finger protein 934 [ Mus musculus (house mouse) ]

Gene ID: 77117, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp934provided by MGI
Official Full Name
zinc finger protein 934provided by MGI
Primary source
MGI:MGI:1924367
See related
Ensembl:ENSMUSG00000074865 AllianceGenome:MGI:1924367
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6720457D02Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in limb mesenchyme. Orthologous to human ZNF101 (zinc finger protein 101) and ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 2.3), placenta adult (RPKM 1.7) and 22 other tissues See more
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Genomic context

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Location:
13 B3; 13 32.74 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (62664609..62727170, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (62516795..62579321, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7245 Neighboring gene zinc finger protein 935 Neighboring gene predicted gene, 21145 Neighboring gene STARR-seq mESC enhancer starr_34772 Neighboring gene protein C1orf43 homolog Neighboring gene STARR-seq mESC enhancer starr_34773 Neighboring gene predicted gene, 24095 Neighboring gene predicted gene, 38639 Neighboring gene zinc finger protein 1008 Neighboring gene STARR-positive B cell enhancer mm9_chr13:62725440-62725741 Neighboring gene predicted gene, 36298

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 782

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162911.2 → NP_001156383.1  zinc finger protein 782 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122357, CT030240
    Consensus CDS
    CCDS88472.1
    UniProtKB/TrEMBL
    K7N6H3
    Related
    ENSMUSP00000099083.6, ENSMUST00000101547.12
    Conserved Domains (4) summary
    COG5048
    Location:178 → 471
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:359 → 379
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 44
    KRAB; KRAB box
    pfam13465
    Location:147 → 171
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001360915.1 → NP_001347844.1  zinc finger protein 782 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon, which results in a frameshift, compared to variant 1. The encoded isoform (3) has a shorter distinct C-terminus and lacks zinc finger domains.
    Source sequence(s)
    AC122357, BY719365
    Consensus CDS
    CCDS88471.1
    UniProtKB/TrEMBL
    A0A1Y7VKB4
    Related
    ENSMUSP00000152804.2, ENSMUST00000222746.2
    Conserved Domains (1) summary
    pfam01352
    Location:4 → 44
    KRAB; KRAB box

  3. NM_175252.5 → NP_780461.3  zinc finger protein 782 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC122357, CT030240
    Consensus CDS
    CCDS88470.1
    UniProtKB/TrEMBL
    A0A1Y7VJM8
    Related
    ENSMUSP00000152492.2, ENSMUST00000220648.2
    Conserved Domains (3) summary
    COG5048
    Location:146 → 439
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115 → 139
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    62664609..62727170 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315637.3 → XP_017171126.1  zinc finger protein 782 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:196 → 489
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:377 → 397
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:22 → 62
    KRAB; KRAB box
    pfam13465
    Location:165 → 189
    zf-H2C2_2; Zinc-finger double domain

  2. XM_030247464.1 → XP_030103324.1  zinc finger protein 782 isoform X3

    UniProtKB/TrEMBL
    A0A1Y7VJM8
    Conserved Domains (3) summary
    COG5048
    Location:146 → 439
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115 → 139
    zf-H2C2_2; Zinc-finger double domain

  3. XM_030247463.2 → XP_030103323.1  zinc finger protein 782 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:183 → 476
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:364 → 384
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:9 → 49
    KRAB; KRAB box
    pfam13465
    Location:152 → 176
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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